Pulegone: An Emerging Oxygenated Cyclic Monoterpene Ketone Scaffold Delineating Synthesis, Chemical Reactivity, and Biological potential.

Autor:	Dhingra AK; Guru Gobind Singh College of Pharmacy, Yamuna Nagar 135001, Haryana, India., Chopra B; Guru Gobind Singh College of Pharmacy, Yamuna Nagar 135001, Haryana, India.
Jazyk:	angličtina
Zdroj:	Recent advances in anti-infective drug discovery [Recent Adv Antiinfect Drug Discov] 2023; Vol. 18 (1), pp. 16-28.
DOI:	10.2174/2772434418666221018090507
Abstrakt:	Pulegone ((R)-5-Methyl-2-(1-methylethylidine) cyclohexanone) is a pharmacologically active, natural monoterpene ketone obtained from leaves and flowering tops of the mint family (Lamiaceae). The aim is to comprise the physicochemical and biological aspects of pulegone. All significant databases were collected via electronic search using Pubmed, Scopus, Web of Science, and Science Direct and were compiled. This review presents the occurrence, chemistry, and modifications of pulegone structure and its effect on the biological system. Pulegone represents various pharmacological properties, i.e., antioxidant, antimicrobial, anti-feeding, antifungal, antiviral, and pesticide activities, and has a significant role as an abortifacient and emmenagogue. Thus, this present review concludes the knowledgeable erudition on pulegone that paves the way for further work. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Databáze:	MEDLINE
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