Transient Sideroblastic Anemia Post-COVID-19 Infection.
| Autor: | Mukhi N; Hematology/Oncology, St. Francis Hospital, Tulsa, USA., Soto LR; Pathology, St. Francis Hospital, Tulsa, USA., Vuppala A; Medicine, St. Francis Hospital, Tulsa, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Oct 13; Vol. 14 (10), pp. e30275. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.30275 |
| Abstrakt: | A 57-year-old gentleman presented to the hospital with progressive fatigue and dyspnea on exertion three months after recovering from COVID-19. He was noted to have severe anemia with reticulocytopenia. After excluding vitamin deficiencies and heavy metal toxicities, a bone marrow aspirate and biopsy were performed, which showed erythroid predominant trilineage maturing hematopoiesis with 79% ring sideroblasts and no dysplasia. SF3B1 mutation was negative. He was diagnosed with sideroblastic anemia and became transfusion-dependent. He was treated with an erythropoiesis-stimulating agent and luspatercept with transient improvement in anemia. After 12 months of treatment, anemia spontaneously improved. Repeat bone marrow biopsy showed hypercellular marrow with 39% ringed sideroblasts. We suspect that this possibly was a delayed manifestation of COVID-19 infection. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Mukhi et al.) |
| Databáze: | MEDLINE |
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