Regional differences and temporal trend analysis of Hepatitis B in Brazil.

Autor: Grandi G; Infectious Diseases Division, Escola Paulista de Medicina, Hospital São Paulo, Universidade Federal de São Paulo, São Paulo, SP, Brazil.; Institute of Mathematics and Statistics, The University of São Paulo, São Paulo, SP, Brazil.; Rua Botucatu, 740-5th floor. Room 507, CEP 04023-062, São Paulo, SP, Brazil., Lopez LF; Discipline of Medical Informatics and LIM-01 HCFMUSP, School of Medicine, The University of São Paulo, São Paulo, SP, Brazil.; Center for Internet Augmented Research and Assessment - CIARA, Florida International University, Florida, USA., Burattini MN; Infectious Diseases Division, Escola Paulista de Medicina, Hospital São Paulo, Universidade Federal de São Paulo, São Paulo, SP, Brazil. mnburatt@gmail.com.; Discipline of Medical Informatics and LIM-01 HCFMUSP, School of Medicine, The University of São Paulo, São Paulo, SP, Brazil. mnburatt@gmail.com.
Jazyk: angličtina
Zdroj: BMC public health [BMC Public Health] 2022 Oct 17; Vol. 22 (1), pp. 1931. Date of Electronic Publication: 2022 Oct 17.
DOI: 10.1186/s12889-022-14296-1
Abstrakt: Background: Burden disease related to chronic HBV infection is increasing worldwide. Monitoring Hepatitis B occurrence is difficult due to intrinsic characteristics of the infection, nonetheless analyzing this information improves strategic planning towards reducing the burden related to chronic infection. In this line of thought, this study aims to analyze national and regional epidemiology of Hepatitis B and it's temporal trends based on Brazilian reported cases.
Methods: Data obtained from the Brazilian National Notifiable Disease Reporting System (SINAN) from 2007 to 2018 were classified by infection status with an original classification algorithm, had their temporal trends analyzed by Joinpoint regression model and were correlated with gender, age and region.
Results: Of the 487,180 hepatitis B cases notified to SINAN, 97.65% had it infection status correctly classified by the new algorithm. Hepatitis B detection rate, gender and age-distribution were different among Brazilian regions. Overall, detection rates remained stable from 2007 to 2018, achieving their maximal value (56.1 cases per 100,000 inhabitants) in North region. However, there were different temporal trends related to different hepatitis B status and age. Women mean age at notification were always inferior to those of men and the difference was higher in Central-West, North and Northeast regions.
Conclusion: Hepatitis B affects heterogeneously different populations throughout Brazilian territory. The differences shown in its temporal trends, regional, gender and age-related distribution helps the planning and evaluation of control measures in Brazil.
(© 2022. The Author(s).)
Databáze: MEDLINE
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