Antibiotic usage practices and its drivers in commercial chicken production in Bangladesh.

Autor: Chowdhury S; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh., Fournié G; Royal Veterinary College, London, United Kingdom., Blake D; Royal Veterinary College, London, United Kingdom., Henning J; The University of Queensland, Brisbane, Australia., Conway P; Nanyang Technological University, Singapore, Singapore., Hoque MA; Chattogram Veterinary and Animal Sciences University, Chittagong, Bangladesh., Ghosh S; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh., Parveen S; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh., Biswas PK; Chattogram Veterinary and Animal Sciences University, Chittagong, Bangladesh., Akhtar Z; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh.; Biosecurity Program, The Kirby Institute, University of New South Wales (UNSW), Sydney, Australia., Islam K; Fleming Fund Country Grant to Bangladesh, DAI Global, LLC, Dhaka, Bangladesh., Islam MA; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh., Rashid MM; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh.; School of Women's and Children's Health, University of New South Wales (UNSW), Sydney, Australia., Pelligand L; Royal Veterinary College, London, United Kingdom., Khan ZH; Fleming Fund Country Grant to Bangladesh, DAI Global, LLC, Dhaka, Bangladesh., Rahman M; Global Health Development, EMPHNET, Dhaka, Bangladesh., Tomley F; Royal Veterinary College, London, United Kingdom., Debnath N; Fleming Fund Country Grant to Bangladesh, DAI Global, LLC, Dhaka, Bangladesh., Chowdhury F; International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2022 Oct 17; Vol. 17 (10), pp. e0276158. Date of Electronic Publication: 2022 Oct 17 (Print Publication: 2022).
DOI: 10.1371/journal.pone.0276158
Abstrakt: Irrational and inappropriate use of antibiotics in commercial chicken production can contribute to the development of antimicrobial resistance. We aimed to assess antibiotic usage in commercial chicken production in Bangladesh, and identify factors associated with this practice. We conducted a large-scale cross-sectional study to collect information on antibiotic usage in commercial chickens from January to May 2021. Structured interviews were conducted with 288 broiler, 288 layer and 192 Sonali (locally-produced cross-bred) farmers in 20 sub-districts across Bangladesh. The frequency of antibiotic usage, the types of antibiotics and purpose of usage were estimated for each production type. Adjusted odds ratios (aOR) were calculated to measure the association between antibiotic usage and factors related to the characteristics of the farms and farmers using multivariable logistic regression models. The proportion of farms, irrespective of their production type, reporting usage of antibiotics in the 24 hours preceding the interview was 41% (n = 314, 95% CI: 37-44%). Forty-five percent (n = 344, 41-48%) reported antibiotic usage in the last 72 hours, 86% (n = 658, 83-88%) in the last 14 days, and almost all farms, 98% (n = 753, 97-99%), had used antibiotics since the start of their production cycle. Use of antibiotics in the 24 hours preceding an interview was more frequently reported in broiler (OR 1.91, 95% CI: 1.36-2.69) and Sonali (OR 1.94, 95% CI: 1.33-2.33) than layer farms. Oxytetracycline (23-31%, depending on production type), doxycycline (18-25%), ciprofloxacin (16-26%) and amoxicillin (16-44%) were the most frequently used antibiotics. Antibiotics were reported to be used for both treatment and prophylactic purposes on most farms (57-67%). Usage of antibiotics in the 24h preceding an interview was significantly associated with the occurrence of any illnesses in chickens (aOR broiler: 41.22 [95% CI:13.63-124.62], layer: aOR 36.45[9.52-139.43], Sonali: aOR 28.47[4.97-162.97]). Antibiotic usage was mainly advised by veterinary practitioners (45-71%, depending on production type), followed by feed dealers (21-40%) and farmers (7-13%). Improvement of chicken health through good farming practices along with changes in key stakeholders (feed dealers and practitioners) attitudes towards antibiotic recommendations to farmers, may help to reduce the levels of antibiotic usage and thus contribute to mitigate antimicrobial resistance.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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