Survival of Patient With Hemorrhagic Meningitis Associated With Inhalation Anthrax.

Autor: Lombarte Espinosa E; Servicio Medicina Intensiva, UCI Polivalente, Hospital Universitario Miguel Servet, Zaragoza, Spain., Villuendas Usón MC; Servicio Microbiología, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain., Arribas García J; Servicio Microbiología, Hospital Comarcal Alcañiz, Teruel, Spain., Jado García I; Laboratorio de Referencia e Investigación en Patógenos Especiales, Centro Nacional de Microbiología. Instituto de Salud Carlos III, Madrid, Spain., Huarte Lacunza R; Servicio de Farmacia Hospitalaria, Hospital Universitario Miguel Servet, Zaragoza, Spain., Zárate Chug P; Servicio Medicina Intensiva, UCI Polivalente, Hospital Universitario Miguel Servet, Zaragoza, Spain., Claraco Vega LM; Servicio Medicina Intensiva, UCI Polivalente, Hospital Universitario Miguel Servet, Zaragoza, Spain., Jesús Santed Andrés M; Servicio Medicina Intensiva, UCI Polivalente, Hospital Universitario Miguel Servet, Zaragoza, Spain., Ríos MJ; Servicio Medicina Intensiva, UCI Polivalente, Hospital Universitario Miguel Servet, Zaragoza, Spain., Cook R; Oak Ridge Institute for Science and Education, CDC Fellowship Program, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Simard JM; Departments of Neurosurgery, Pathology and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA., Boyer AE; Division of Laboratory Sciences, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Rezusta A; Servicio Microbiología, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain.
Jazyk: angličtina
Zdroj: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Oct 17; Vol. 75 (Suppl 3), pp. S364-S372.
DOI: 10.1093/cid/ciac531
Abstrakt: This report describes a 49-year-old male construction worker who acquired a Bacillus anthracis infection after working on a sheep farm. He experienced a severe respiratory infection, septic shock, and hemorrhagic meningoencephalitis with severe intracranial hypertension. After several weeks with multiple organ dysfunction syndrome, he responded favorably to antibiotic treatment. Three weeks into his hospitalization, an intracranial hemorrhage and cerebral edema led to an abrupt deterioration in his neurological status. A single dose of raxibacumab was added to his antimicrobial regimen on hospital day 27. His overall status, both clinical and radiographic, improved within a few days. He was discharged 2 months after admission and appears to have fully recovered.
(Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022. This work is written by (a) US Government employee(s) and is in the public domain in the US.)
Databáze: MEDLINE