Prevalence and Risk Factors of Osteoporosis in Saudi End-Stage Renal Disease Patients on Hemodialysis.

Autor:	Mahzari MM; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia., Alibrahim AR; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia., Alghamdi NA; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia., Alsadhan MA; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia., Almoamary SM; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia., Masuadi EM; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia., Al Shahrani AS; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Saudi journal of medicine & medical sciences [Saudi J Med Med Sci] 2022 Sep-Dec; Vol. 10 (3), pp. 259-265. Date of Electronic Publication: 2022 Aug 22.
DOI:	10.4103/sjmms.sjmms_639_21
Abstrakt:	Background: Osteoporosis is characterized by a decrease in bone mineral density, thereby increasing the risk of pathological fractures. It is a common complication of chronic kidney disease. However, there is limited local data on the prevalence of osteoporosis in end-stage renal disease. Objective: The current study evaluated the epidemiology of osteoporosis in end-stage rental disease patients at a Saudi Arabian tertiary care center. Methods: This cross-sectional retrospective study was conducted using data obtained between 1 January 2016 and 31 December 2019 at the Dialysis Center at King Abdulaziz Medical City, Riyadh, Saudi Arabia. End-stage rental disease patients who were aged ≥50 years and underwent hemodialysis for at least 1 year were included, while those with documented metabolic bone disease and absence of bone mineral density data were excluded. Results: Sixty-four end-stage rental disease patients undergoing hemodialysis met the inclusion criteria. The patients underwent bone mineral density measurement at the discretion of the treating physician. The mean patients' age was 73 ± 11.5 years and 76% were women. The overall prevalence of osteoporosis was 37.5%, and it was similarly distributed among women and men (38.8% and 33.3%, respectively). Nine of the 15 male patients (60%) and 24 of the 49 female patients (49%) had fractures. Twenty-five (39%) patients used glucocorticoids. Osteoporosis was most commonly identified in the femoral neck (26.2%), followed by proximal femur (19.4%), and lumbar spine (18.8%). A high rate of osteoporosis was significantly associated with older age and being underweight. Conclusion: A high rate of low bone mineral density was demonstrated in end-stage renal disease patients. The femoral neck was the most common osteoporosis site in this patient population, and advanced age and underweight were possible risk factors for low bone mass. Competing Interests: There are no conflicts of interest. (Copyright: © 2022 Saudi Journal of Medicine & Medical Sciences.)
Databáze:	MEDLINE
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