Pediatric body mass index trajectories and the risk of hypertension among adolescents in China: a retrospective cohort study.

Autor: Ge WX; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China., Han D; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, 215004, China., Ding ZY; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, 215004, China.; Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China., Yi LP; Department of Epidemiology, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China., Yang ZQ; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China., Wang XN; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China., Xiao Y; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China., Liang F; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China., Hai B; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, 215004, China., Lv HL; State Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, China., Shen H; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, 215004, China.; State Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.; Suzhou Institute of Advanced Study in Public Health, Gusu School, Nanjing Medical University, Suzhou, China., Yang HB; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, 215004, China.; State Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.; Suzhou Institute of Advanced Study in Public Health, Gusu School, Nanjing Medical University, Suzhou, China., Yin JY; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China. jyyin@suda.edu.cn., Hu J; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, 215004, China. hujia200606@163.com.; State Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, China. hujia200606@163.com.; Suzhou Institute of Advanced Study in Public Health, Gusu School, Nanjing Medical University, Suzhou, China. hujia200606@163.com.
Jazyk: angličtina
Zdroj: World journal of pediatrics : WJP [World J Pediatr] 2023 Jan; Vol. 19 (1), pp. 76-86. Date of Electronic Publication: 2022 Oct 16.
DOI: 10.1007/s12519-022-00626-1
Abstrakt: Background: The impact of pediatric body mass index (BMI) trajectories on the risk of adolescent hypertension (HTN) determined by three separate visits remains unclear. This longitudinal study aims to identify potential pediatric sex-specific BMI trajectories and to assess their associations with HTN and HTN subtypes.
Methods: Based on the Health Promotion Program for Children and Adolescents (HPPCA) in Suzhou, China, a total of 24,426 participants who had initial normal blood pressure (BP) and had at least four BMI measurements during 2012-2020 were included. HTN was defined as simultaneously having three separate visits of elevated BP in 2020. Latent class growth models were used to explore sex-specific BMI trajectories, whose associations with HTN and HTN subtypes were further examined by logistic regression.
Results: The incidence of HTN determined through three separate visits was 3.34%. Four trajectories were identified for both sexes: low BMI increasing, medium BMI increasing, high BMI increasing, and highest BMI increasing. Compared to the medium BMI increasing group, the odds ratio (95% confidential interval) for developing adolescent HTN of the low, high, and highest BMI increasing groups among boys were 0.54 (0.39, 0.75), 1.90 (1.44, 2.51), and 2.89 (1.90, 4.39), respectively; and the corresponding values for girls were 0.66 (0.48, 0.90), 2.30 (1.72, 3.09), and 4.71 (3.06, 7.26). Similar gradually elevated associations between different trajectories with isolated systolic hypertension, systolic and diastolic hypertension were observed.
Conclusion: Current results emphasized the adverse effects of stable high BMI on HTN and the benefits of maintaining normal weight throughout childhood.
(© 2022. Children's Hospital, Zhejiang University School of Medicine.)
Databáze: MEDLINE
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