Efficacy of Individualized Homeopathic Medicines in the Treatment of Cervical Spondylosis: A Double-Blind, Randomized, Placebo-Controlled Trial.

Autor:	Tomar M; Department of Organon of Medicine and Homeopathic Philosophy, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Bhowmik NC; Department of Organon of Medicine and Homeopathic Philosophy, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Singh S; National Institute of Homoeopathy, Ministry of AYUSH, Government of Indiae, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Sadhukhan S; Department of Organon of Medicine and Homeopathic Philosophy, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Michael J; Department of Organon of Medicine and Homeopathic Philosophy, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Parewa M; Department of Repertory, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Rai S; Department of Organon of Medicine and Homeopathic Philosophy, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Gupta B; Department of Pediatrics, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Vashisht H; Department of Repertory, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Misra P; Department of Materia Medica, National Institute of Homoeopathy, Ministry of AYUSH, Government of India, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India., Koley M; East Bishnupur State Homoeopathic Dispensary, Chandi Daulatabad Block Primary Health Centre, Under Department of Health & Family Welfare, Government of West Bengal, Kolkata, India., Saha S; Department of Repertory, D. N. De Homoeopathic Medical College and Hospital, Affiliated to the West Bengal University of Health Sciences, Government of West Bengal, Kolkata, India.
Jazyk:	angličtina
Zdroj:	Complementary medicine research [Complement Med Res] 2023; Vol. 30 (1), pp. 26-36. Date of Electronic Publication: 2022 Oct 14.
DOI:	10.1159/000527523
Abstrakt:	Introduction: Cervical spondylosis (CS) is a degenerative condition of the cervical spine, with approximately 80-90% of people suffering from disc degeneration by the age of 50 years. This trial attempts at evaluating the efficacy of individualized homeopathic medicines (IHMs) against placebos in the treatment of CS. Methods: A 3-month, double-blind, randomized, placebo-controlled trial was conducted at the Organon of Medicine outpatient department of the National Institute of Homoeopathy, India. Patients were randomized to receive either IHMs (n = 70) or identical-looking placebos (n = 70) in the mutual context of concomitant conservative and standard physiotherapeutic care. Primary outcome measures were 0-10 Numeric Rating Scales (NRSs) for pain, stiffness, numbness, tingling, weakness, and vertigo, and the secondary outcome was the Neck Disability Index (NDI), measured at baseline and every month until 3 months. The intention-to-treat sample was analyzed to detect group differences and effect sizes. Results: Overall, improvements were clinically significant and higher in the IHM group than the placebo group, but group differences were statistically nonsignificant with small effect sizes (all p > 0.05, two-way repeated measure analysis of variance). After 2 months of time points, improvements observed in the IHM group were significantly higher than placebo on a few occasions (e.g., pain NRS: p < 0.001; stiffness NRS: p = 0.024; weakness NRS: p = 0.003). Sulfur (n = 21; 15%) was the most frequently prescribed medication. No harm, unintended effects, or any serious adverse events were reported from either group. Conclusions: An encouraging but nonsignificant direction of effect was elicited favoring IHMs against placebos in the treatment of CS. (© 2022 S. Karger AG, Basel.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu