Molecular regulation, breed differences and genes involved in stress control in farm animals.

Autor: Durosaro SO; Department of Animal Breeding and Genetics, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria; Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA. Electronic address: durosaroso@funaab.edu.ng., Iyasere OS; Department of Animal Physiology, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria., Ilori BM; Department of Animal Breeding and Genetics, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria., Oyeniran VJ; Department of Animal Physiology, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria., Ozoje MO; Department of Animal Breeding and Genetics, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria.
Jazyk: angličtina
Zdroj: Domestic animal endocrinology [Domest Anim Endocrinol] 2023 Jan; Vol. 82, pp. 106769. Date of Electronic Publication: 2022 Sep 20.
DOI: 10.1016/j.domaniend.2022.106769
Abstrakt: Stress is a state of disturbed homeostasis evoking a multiplicity of somatic and mental adaptive reactions resulting from any of the 5 freedoms of animals being violated. Many environmental forces disrupt homeostasis in farm animals, such as extreme temperatures, poor nutrition, noise, hunger, and thirst. During stressful situations, neuronal circuits in the limbic system and prefrontal cortex are activated, which lead to the release of adrenalin and noradrenalin. The hormones released during stress are needed for adaptation to acute stress and are regulated by many genes. This review examined molecular regulation, breed differences, and genes involved in stress control in farm animals. Major molecular regulation of stress, such as oxidative, cytosolic heat shock, unfolded protein, and hypoxic responses, were discussed. The responses of various poultry, ruminant, and pig breeds to different stress types were also discussed. Gene expressions and polymorphisms in the neuroendocrine and neurotransmitter pathways were also elucidated. The information obtained from this review will help farmers mitigate stress in farm animals through appropriate breed and gene-assisted selection. Also, information obtained from this review will add to the field of stress genetics since stress is a serious welfare issue in farm animals.
(Copyright © 2022. Published by Elsevier Inc.)
Databáze: MEDLINE
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