Risk Factor Identification for Delayed Gastric Emptying after Distal Pancreatectomy-An Evaluation of 1688 Patients Based on the German StuDoQ|Pancreas Registry.

Autor: Fahlbusch T; Department of General and Visceral Surgery, St. Josef Hospital, Ruhr-University Bochum, 44801 Bochum, Germany., Höhn P; Department of General and Visceral Surgery, St. Josef Hospital, Ruhr-University Bochum, 44801 Bochum, Germany., Klinger C; Deutsche Gesellschaft für Allgemein-und Viszeralchirurgie, 10117 Berlin, Germany., Werner J; Department of General, Visceral, and Transplant Surgery, University Hospital Munich, LMU, 80539 Munich, Germany., Keck T; Department of Surgery, University Hospital Schleswig-Holstein, Campus Lübeck, 23562 Lübeck, Germany., Friess H; Klinik und Poliklinik für Chirurgie, Klinikum Rechts der Isar, TUM München, 80333 München, Germany., Köninger J; Klinik für Allgemein-, Viszeral-, Thorax- und Transplantationschirurgie, Katharinenhospital Stuttgart, 70174 Stuttgart, Germany., Kraus TW; Allgemein-, Viszeral- und Minimalinvasive Chirurgie, Nordwestkrankenhaus Frankfurt, 60488 Frankfurt am Main, Germany., Alsfasser G; Klinik und Poliklinik für Allgemein-, Viszeral-, Thorax-, Gefäß- und Transplantationschirurgie, Universitätsmedizin Rostock, 18057 Rostock, Germany., Padberg W; Allgemein-, Viszeral-, Thorax-, Transplantations- und Kinderchirurgie, Universitätsklinikum Gießen Marburg, Standort Gießen, 35392 Gießen, Germany., Ritz JP; Klinik für Allgemein- und Viszeralchirurgie, Helios Kliniken Schwerin, 19055 Schwerin, Germany., Uhl W; Department of General and Visceral Surgery, St. Josef Hospital, Ruhr-University Bochum, 44801 Bochum, Germany., Belyaev O; Department of General and Visceral Surgery, St. Josef Hospital, Ruhr-University Bochum, 44801 Bochum, Germany.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Sep 21; Vol. 11 (19). Date of Electronic Publication: 2022 Sep 21.
DOI: 10.3390/jcm11195539
Abstrakt: Delayed gastric emptying (DGE) ranks as one of the most frequent complications in pancreatic surgery. It leads to increased costs for healthcare systems, lengthened hospital stays and reduced quality of life. Data about DGE after distal pancreatectomy (DP) are scarce. The StuDoQ|Pancreas registry of the German Society of General and Visceral Surgery provided data of patients who underwent distal pancreatectomy from 1 January 2014 to 31 December 2018. The retrospective evaluation included comprehensive data: 1688 patients were enrolled; DGE occurred 160 times (9.5%); grade “A” was reported for 98 (61.3%), grade “B” for 41 (25.6%) and grade “C” for 21 (13.1%) patients. In univariate analysis pancreatic fistulas were associated with higher frequencies of intraabdominal abscesses (9.1% vs. 2%, p > 0.001), postpancreatectomy haemorrhage (8.1% vs. 3.7%, >0.001) and DGE (14.5% vs. 6%, p < 0.001). According to multivariate analysis, “abscesses with invasive therapy” (p < 0.001), “other surgical complications” (p < 0.001), prolonged “stays in ICU” (p < 0.001), lengthened duration of surgery (p < 0.001) and conventional surgery (p = 0.007) were identified as independent risk factors for DGE. Perioperative and postoperative factors were identified as risk factors for DGE. Following research should examine this highly relevant topic in a prospective, register-based manner. As there is no causal therapy for DGE, its avoidance is of major importance.
Databáze: MEDLINE
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