Use of Immune Checkpoint Inhibitors in Elderly Patients With Chronic Kidney Disease and Renal Cell Carcinoma Metastasis of the Parotid Gland: Case Report and Review of the Literature.
| Autor: | Parosanu A; Oncology, Elias Emergency University Hospital, Bucharest, ROU., Orlov Slavu C; Oncology, Elias Emergency University Hospital, Bucharest, ROU., Pirlog C; Oncology, Elias Emergency University Hospital, Bucharest, ROU., Stanciu IM; Oncology, Elias Emergency University Hospital, Bucharest, ROU., Nitipir C; Oncology, Elias Emergency University Hospital, Bucharest, ROU. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Sep 06; Vol. 14 (9), pp. e28868. Date of Electronic Publication: 2022 Sep 06 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.28868 |
| Abstrakt: | Renal cell carcinoma metastasis of the parotid gland is extremely rare, and the present literature review found only 23 cases reported in the last two decades. We present a case of a 75-year-old woman with a colon cancer history who had parotid gland metastasis as the first manifestation of second primary kidney cancer. The presence of multiple comorbidities affected medical decision-making. Therefore the patient was treated primarily with immunotherapy. After four cycles of dual immune checkpoint blockade, this advanced patient still benefited and was changed to nivolumab monotherapy as maintenance therapy. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Parosanu et al.) |
| Databáze: | MEDLINE |
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