Anopheles gambiae s.l. swarms trapping as a complementary tool against residual malaria transmission in eastern Gambia.

Autor: Assogba BS; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia. Sessinou-Benoit.Assogba@lshtm.ac.uk., Sillah S; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Opondo KO; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Cham ST; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Camara MM; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Jadama L; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Camara L; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Ndiaye A; Laboratoire d'Ecologie Vectorielle et Parasitaire, Faculté des Sciences et Techniques, Université Cheikh Anta Diop, Dakar, Sénégal., Wathuo M; Statistic and Bioinformatic Department, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Jawara M; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Diabaté A; Institut de Recherche en Science de la Santé/Centre Muraz, BP 545, Bobo-Dioulasso, Burkina Faso., Achan J; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., D'Alessandro U; Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia. Umberto.Dalessandro@lshtm.ac.uk.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2022 Oct 12; Vol. 12 (1), pp. 17057. Date of Electronic Publication: 2022 Oct 12.
DOI: 10.1038/s41598-022-21577-7
Abstrakt: Malaria remains a major health problem and vector control is an essential approach to decrease its burden, although it is threatened by insecticide resistance. New approaches for vector control are needed. The females of Anopheles gambiae s.l. mate once in their life and in the swarms formed by males. Trapping swarms of Anopheles gambiae s.l. males is a potential new intervention for vector control, alternative to the use of insecticides, as it would disrupt mating . The proof-of-concept pilot study aiming at investigating swarm trapping as a potential vector control intervention, was carried out in 6 villages as in eastern Gambia. Swarms of Anopheles gambiae s.l. were identified and their size, height, and duration determined during the baseline year. Swarm trapping by local volunteers was implemented the following transmission season in 4 villages while the other 2 villages were taken as controls. Entomological outcomes were monitored by Human Landing Catches and Pyrethrum Spray Catches. A cross-sectional survey to determine malaria prevalence was carried out at the peak of the malaria transmission season for two consecutive years. At baseline, 23 swarming sites of Anopheles gambiae s.l. were identified. Before the intervention, mean indoor resting density per house and malaria prevalence were similar between control and intervention villages. Following the intervention, Anopheles gambiae s.l. indoor resting density was 44% lower in intervention than in control villages (adj IRR: 0.0.56; 95% CI 0.47-0.68); the odds of malaria infections were 68% lower in intervention than in control villages (OR: 0.32; 95% CI 0.11-0.97). Swarm trapping seems to be a promising, community-based vector control intervention that could reduce malaria prevalence by reducing vector density. Such results should be further investigated and confirmed by larger cluster-randomized trials.
(© 2022. The Author(s).)
Databáze: MEDLINE
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