Persistent COVID-19 symptoms 1 year after hospital discharge: A prospective multicenter study.

Autor: Aranda J; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Oriol I; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL); L'Hospitalet de Llobregat, Barcelona, Spain.; Faculty of Medicine and Health Sciences, Clinical Science Department, University of Barcelona, Barcelona, Spain., Feria L; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Abelenda G; Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain., Rombauts A; Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain., Simonetti AF; Hospital Sant Camil, Sant Pere de Ribes, Barcelona, Spain., Catalano C; Hospital Sant Camil, Sant Pere de Ribes, Barcelona, Spain., Pallarès N; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC; CB21/13/00009), Instituto de Salud Carlos III, Madrid, Spain., Martín M; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Vàzquez N; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Vall-Llosera E; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Rhyman N; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Suárez RC; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Nogué M; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Loureiro-Amigo J; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Coloma A; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Ceresuela L; Consorci Sanitari Integral-Complex Hospitalari Moisès Broggi, Sant Joan Despí, Barcelona, Spain., Carratalà J; Bellvitge Biomedical Research Institute (IDIBELL); L'Hospitalet de Llobregat, Barcelona, Spain.; Faculty of Medicine and Health Sciences, Clinical Science Department, University of Barcelona, Barcelona, Spain.; Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC; CB21/13/00009), Instituto de Salud Carlos III, Madrid, Spain.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2022 Oct 10; Vol. 17 (10), pp. e0275615. Date of Electronic Publication: 2022 Oct 10 (Print Publication: 2022).
DOI: 10.1371/journal.pone.0275615
Abstrakt: Objective: To determine the health status and exercise capacity of COVID-19 survivors one year after hospital discharge.
Methods: This multicenter prospective study included COVID-19 survivors 12 months after hospital discharge. Participants were randomly selected from a large cohort of COVID-19 patients who had been hospitalized until 15th April 2020. They were interviewed about persistent symptoms, underwent a physical examination, chest X-ray, and a 6-minute walk test (6MWT). A multivariate analysis was performed to determine the risk factors for persistent dyspnea.
Results: Of the 150 patients included, 58% were male and the median age was 63 (IQR 54-72) years. About 82% reported ≥1 symptoms and 45% had not recovered their physical health. The multivariate regression analysis revealed that the female sex, chronic obstructive pulmonary disease, and smoking were independent risk factors for persistent dyspnea. Approximately 50% completed less than 80% of the theoretical distance on the 6MWT. Only 14% had an abnormal X-ray, showing mainly interstitial infiltrates. A third of them had been followed up in outpatient clinics and 6% had undergone physical rehabilitation.
Conclusion: Despite the high rate of survivors of the first wave of the COVID-19 pandemic with persistent symptomatology at 12 months, the follow-up and rehabilitation of these patients has been really poor. Studies focusing on the role of smoking in the persistence of COVID-19 symptoms are lacking.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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