Myocardial infarction with non-obstructive coronary arteries in a patient double-seropositive for anti-glomerular basement membrane and anti-neutrophil cytoplasmic antibodies: A case report.

Autor: Krall M; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Gollmer J; Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Pollheimer MJ; Institute of Pathology, Medical University of Graz, Graz, Austria., Reiter C; Division of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria., Kolland M; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Kirsch AH; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Kronbichler A; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Eller K; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Rosenkranz AR; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Odler B; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Jazyk: angličtina
Zdroj: Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2022 Sep 23; Vol. 9, pp. 893742. Date of Electronic Publication: 2022 Sep 23 (Print Publication: 2022).
DOI: 10.3389/fcvm.2022.893742
Abstrakt: We report a case of a patient double-seropositive for anti-glomerular basement membrane (anti-GBM) and anti-neutrophil cytoplasmic antibodies (ANCA) who reported retrosternal chest pain during a regular hemodialysis session associated with ST-segment depression in electrocardiogram and an increase of serum high-sensitivity troponin T. Urgent coronary angiography excluded obstructive coronary artery disease, suggesting the diagnosis of ischemia with non-obstructive coronary arteries. This case illustrates an unusual presentation of cardiovascular involvement in a patient with double-positive ANCA/anti-GBM disease, emphasizing the possible relevance of coronary microvascular dysfunction and the need for close cardiovascular follow-up in this patient population.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Krall, Gollmer, Pollheimer, Reiter, Kolland, Kirsch, Kronbichler, Eller, Rosenkranz and Odler.)
Databáze: MEDLINE