Systemic lupus erythematosus myocarditis after COVID-19 vaccination.
| Autor: | Sogbe M; Internal Medicine Department, Clínica Universidad de Navarra, Pamplona, Spain., Blanco-Di Matteo A; Internal Medicine Department, Clínica Universidad de Navarra, Pamplona, Spain., Di Frisco IM; Pulmonary Medicine Department, Clínica Universidad de Navarra, Pamplona, Spain., Bastidas JF; Nuclear Medicine Department, Clínica Universidad de Navarra, Pamplona, Spain., Salterain N; Department of Cardiology, Clínica Universidad de Navarra, Pamplona, Spain., Gavira JJ; Department of Cardiology, Clínica Universidad de Navarra, Pamplona, Spain. |
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| Jazyk: | angličtina |
| Zdroj: | Reumatologia clinica [Reumatol Clin] 2023 Feb; Vol. 19 (2), pp. 114-116. Date of Electronic Publication: 2022 Jul 28. |
| DOI: | 10.1016/j.reuma.2022.06.003 |
| Abstrakt: | Introduction: Cases of acute myocarditis have been after administration of the BNT162b2 and Ad26.COV2.S vaccine. Objective: Describe another possible mechanism of myocarditis after COVID-19 vaccination. Case Presentation: We describe the clinical case of a 72-year-old female with pleuritic chest pain one week after the third of the BNT162b2 mRNA vaccine. Serological tests for cardiotropic pathogens were negative, and autoimmunity screening was positive with anti-nuclear antibody (ANA) in 1:160 dilution, Anti-double-stranded DNA (anti-dsDNA), and anti-histone antibodies. 18 F-fluoro-deoxy-glucose (FDG) positron emission tomography/computed tomography (PET/CT) showed a focal myocardial and pericardial inflammatory process in the cardiac apex. Results and Discussion: Systemic lupus erythematosus (SLE) diagnosis was made with myocardial affection. As far as we know, this is the first report of a case of lupus myocarditis after the COVID-19 vaccine. Conclusion: Given the pathogenic rationales, the association between SLE and myocarditis should be considered. (© 2022 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.) |
| Databáze: | MEDLINE |
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