Magnetically recoverable Fe 3 O 4 nanocatalyst for the synthesis of biodynamically significant 1H-pyrazolo[1,2-b]phthalazine-5,10-diones derivatives and its DFT study.

Autor: Ansari MD; Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Allahabad, 211002, India., Sagir H; Department of Chemistry, Paliwal P.G. College, Shikohabad, 205135, India., Yadav VB; Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Allahabad, 211002, India., Yadav N; Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Allahabad, 211002, India., Verma A; Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Allahabad, 211002, India., Shakya S; Department of Chemistry, Aligarh Muslim University, Aligarh, India., Singh M; Department of Chemistry, IIT BHU, Varanasi, India., Siddiqui IR; Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Allahabad, 211002, India. dr.irsiddiqui@gmail.com.
Jazyk: angličtina
Zdroj: Molecular diversity [Mol Divers] 2023 Aug; Vol. 27 (4), pp. 1853-1866. Date of Electronic Publication: 2022 Oct 07.
DOI: 10.1007/s11030-022-10532-3
Abstrakt: An environmentally sustainable and proficient method is reported for the synthesis of medicinally important pyrazolo[1,2-b] phthalazine dione derivatives by aqueous micellar medium catalysed by Fe 3 O 4 NPs. Dialkyl acetylenedicarboxylate with isocyanides in the presence of phthalhydrazide is used as starting material. The main advantages of this protocol are the availability of starting materials, short reaction times, green solvents and practical simplicity.
(© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
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