Hematologic Malignancies Patients Face High Symptom Burden and Are Lately Referred to Palliative Consultation: Analysis of a Single Center Experience.

Autor: Ebert RPC; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil., Magnus MM; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil., Toro P; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil., Manoel FG; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil., Costa FF; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil., Olalla Saad ST; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil., de Melo Campos P; Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro- UNICAMP, Campinas, Brazil.
Jazyk: angličtina
Zdroj: The American journal of hospice & palliative care [Am J Hosp Palliat Care] 2023 Jul; Vol. 40 (7), pp. 761-764. Date of Electronic Publication: 2022 Oct 07.
DOI: 10.1177/10499091221132285
Abstrakt: Although hematologic neoplasms have been on the vanguard of cancer therapies that led to notable advances in therapeutic efficacy, many patients face significant symptom burden, which make them eligible for early palliative care (PC) integration. However, previous reports demonstrated that hematological malignancies receive more aggressive care at the end-of-life and are less likely to receive care from specialist palliative services compared to solid tumors. Our aim was to characterize symptom burden, performance status and clinical characteristics of a cohort of hematologic malignancies patients referred to PC outpatient consultation, according to their diagnosis. Fifty-nine hematological malignancies patients referred to PC   consultation between January 2018 and September 2021 were included. Clinical and laboratory data were evaluated retrospectively by medical charts analysis. Patients exhibited high ESAS and reduced PPS scores at the time of PC referral. Acute leukemia and multiple myeloma patients had the highest symptom burden scores; in spite of this, median time from the first PC consultation until death was only 3 and 4 months, respectively. In conclusion, we identified that hematologic neoplasms patients are highly symptomatic and are frequently referred to PC in end stages of their disease.
Databáze: MEDLINE