The Catalan Surveillance Network of SARS-CoV-2 in Sewage: design, implementation, and performance.

Autor: Guerrero-Latorre L; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain.; Universitat de Girona, 17003, Girona, Catalonia, Spain., Collado N; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain.; Universitat de Girona, 17003, Girona, Catalonia, Spain., Abasolo N; Centre for Omic Sciences (COS), Joint Unit Universitat Rovira i Virgili-EURECAT, Unique Scientific and Technical Infrastructures (ICTS), Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Anzaldi G; Applied Artificial Intelligence Technological Unit, Eurecat, Centre Tecnològic de Catalunya, Science and Technology Park, H3, 25003, Lleida, Catalonia, Spain., Bofill-Mas S; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Bosch A; Enteric Virus Laboratory, Section of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain.; Research Institute of Nutrition and Food Safety (INSA), University of Barcelona, 08921, Santa Coloma de Gramenet, Catalonia, Spain., Bosch L; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain.; Universitat de Girona, 17003, Girona, Catalonia, Spain., Busquets S; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain.; Universitat de Girona, 17003, Girona, Catalonia, Spain., Caimari A; Biotechnology Area, Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Canela N; Centre for Omic Sciences (COS), Joint Unit Universitat Rovira i Virgili-EURECAT, Unique Scientific and Technical Infrastructures (ICTS), Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Carcereny A; Enteric Virus Laboratory, Section of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain.; Research Institute of Nutrition and Food Safety (INSA), University of Barcelona, 08921, Santa Coloma de Gramenet, Catalonia, Spain., Chacón C; Public Health Agency of Catalonia (ASPCAT), Roc Boronat 81-95, 08005, Barcelona, Catalonia, Spain., Ciruela P; Public Health Agency of Catalonia (ASPCAT), Roc Boronat 81-95, 08005, Barcelona, Catalonia, Spain., Corbella I; Public Health Agency of Catalonia (ASPCAT), Roc Boronat 81-95, 08005, Barcelona, Catalonia, Spain., Domingo X; Applied Artificial Intelligence Technological Unit, Eurecat, Centre Tecnològic de Catalunya, Science and Technology Park, H3, 25003, Lleida, Catalonia, Spain., Escoté X; Technological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Espiñeira Y; Applied Artificial Intelligence Technological Unit, Eurecat, Centre Tecnològic de Catalunya, Science and Technology Park, H3, 25003, Lleida, Catalonia, Spain., Forés E; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Gandullo-Sarró I; Catalan Water Agency (ACA), Provença, 260, 08008, Barcelona, Catalonia, Spain., Garcia-Pedemonte D; Enteric Virus Laboratory, Section of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain.; Research Institute of Nutrition and Food Safety (INSA), University of Barcelona, 08921, Santa Coloma de Gramenet, Catalonia, Spain., Girones R; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Guix S; Enteric Virus Laboratory, Section of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain.; Research Institute of Nutrition and Food Safety (INSA), University of Barcelona, 08921, Santa Coloma de Gramenet, Catalonia, Spain., Hundesa A; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Itarte M; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Mariné-Casadó R; Technological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Martínez A; Public Health Agency of Catalonia (ASPCAT), Roc Boronat 81-95, 08005, Barcelona, Catalonia, Spain., Martínez-Puchol S; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Mas-Capdevila A; Technological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Mejías-Molina C; Laboratory of Viruses Contaminants of Water and Food, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain., Rafa MMI; Catalan Water Agency (ACA), Provença, 260, 08008, Barcelona, Catalonia, Spain., Munné A; Catalan Water Agency (ACA), Provença, 260, 08008, Barcelona, Catalonia, Spain., Pintó RM; Enteric Virus Laboratory, Section of Microbiology, Virology and Biotechnology, Department of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, 08028, Barcelona, Catalonia, Spain.; Research Institute of Nutrition and Food Safety (INSA), University of Barcelona, 08921, Santa Coloma de Gramenet, Catalonia, Spain., Pueyo-Ros J; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain.; Universitat de Girona, 17003, Girona, Catalonia, Spain., Robusté-Cartró J; Catalan Water Agency (ACA), Provença, 260, 08008, Barcelona, Catalonia, Spain., Rusiñol M; Institute of Environmental Assessment & Water Research (IDAEA), CSIC, Barcelona, Catalonia, Spain., Sanfeliu R; Applied Artificial Intelligence Technological Unit, Eurecat, Centre Tecnològic de Catalunya, Science and Technology Park, H3, 25003, Lleida, Catalonia, Spain., Teichenné J; Technological Unit of Nutrition and Health, Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Torrell H; Centre for Omic Sciences (COS), Joint Unit Universitat Rovira i Virgili-EURECAT, Unique Scientific and Technical Infrastructures (ICTS), Eurecat, Centre Tecnològic de Catalunya, Avinguda Universitat 1, 43204, Reus, Catalonia, Spain., Corominas L; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain.; Universitat de Girona, 17003, Girona, Catalonia, Spain., Borrego CM; Catalan Institute for Water Research (ICRA), Emili Grahit 101, 17003, Girona, Catalonia, Spain. cborrego@icra.cat.; Group of Molecular Microbial Ecology, Institute of Aquatic Ecology, University of Girona, 17003, Girona, Catalonia, Spain. cborrego@icra.cat.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2022 Oct 06; Vol. 12 (1), pp. 16704. Date of Electronic Publication: 2022 Oct 06.
DOI: 10.1038/s41598-022-20957-3
Abstrakt: Wastewater-based epidemiology has shown to be an efficient tool to track the circulation of SARS-CoV-2 in communities assisted by wastewater treatment plants (WWTPs). The challenge comes when this approach is employed to help Health authorities in their decision-making. Here, we describe the roadmap for the design and deployment of SARSAIGUA, the Catalan Surveillance Network of SARS-CoV-2 in Sewage. The network monitors, weekly or biweekly, 56 WWTPs evenly distributed across the territory and serving 6 M inhabitants (80% of the Catalan population). Each week, samples from 45 WWTPs are collected, analyzed, results reported to Health authorities, and finally published within less than 72 h in an online dashboard ( https://sarsaigua.icra.cat ). After 20 months of monitoring (July 20-March 22), the standardized viral load (gene copies/day) in all the WWTPs monitored fairly matched the cumulative number of COVID-19 cases along the successive pandemic waves, showing a good fit with the diagnosed cases in the served municipalities (Spearman Rho = 0.69). Here we describe the roadmap of the design and deployment of SARSAIGUA while providing several open-access tools for the management and visualization of the surveillance data.
(© 2022. The Author(s).)
Databáze: MEDLINE
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