Re-emergence of dengue, chikungunya, and Zika viruses in 2021 after a 10-year gap in Gabon.

Autor:	Ushijima Y; Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan., Abe H; Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan., Mbadinga MJVM; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Ondo GN; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Bikangui R; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Agnandji ST; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany., Lell B; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany.; Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria., Yasuda J; Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.; Department of Emerging Infectious Diseases, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, Nagasaki, Japan.; Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Jazyk:	angličtina
Zdroj:	IJID Regions (Online) [IJID Reg] 2022 Sep 05; Vol. 5, pp. 68-71. Date of Electronic Publication: 2022 Sep 05 (Print Publication: 2022).
DOI:	10.1016/j.ijregi.2022.08.013
Abstrakt:	Mosquito-borne viral infections are a major concern in endemic areas, such as Africa. Although outbreaks have been reported throughout Africa, only a few surveillance studies have been conducted in Gabon since the outbreaks of dengue virus (DENV) and chikungunya virus (CHIKV) in 2010. Therefore, the current situation is unknown. This study aimed to investigate the presence of arboviruses, especially DENV (serotypes 1-4), CHIKV, and Zika virus (ZIKV), in Gabon, Central Africa. Between 2020 and 2021, we collected 1060 serum samples from febrile patients and screened them against viruses using reverse transcription-quantitative PCR. We detected two DENV serotypes 1 (DENV-1), one CHIKV, and one ZIKV, and subsequently analyzed the genome sequences. To determine the genetic diversity and transmission route of the viruses, phylogenetic analysis was performed using complete or partial genome sequences. The DENV-1 and CHIKV strains detected in this study were closely related to the previous Gabonese strains, whereas the recent ZIKV strain was genetically different from a strain detected in 2007 in Gabon. This study provides new genomic information on DENV-1, CHIKV, and ZIKV that were detected in Gabon and insight into the circulation of the viruses in the country and their introduction from neighboring African countries. (© 2022 The Author(s).)
Databáze:	MEDLINE
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