Shedding light on neurons: optical approaches for neuromodulation.

Autor: Jiang S; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA., Wu X; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA., Rommelfanger NJ; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.; Department of Applied Physics, Stanford University, Stanford, CA 94305, USA., Ou Z; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA., Hong G; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
Jazyk: angličtina
Zdroj: National science review [Natl Sci Rev] 2022 Jan 18; Vol. 9 (10), pp. nwac007. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2022).
DOI: 10.1093/nsr/nwac007
Abstrakt: Today's optical neuromodulation techniques are rapidly evolving, benefiting from advances in photonics, genetics and materials science. In this review, we provide an up-to-date overview of the latest optical approaches for neuromodulation. We begin with the physical principles and constraints underlying the interaction between light and neural tissue. We then present advances in optical neurotechnologies in seven modules: conventional optical fibers, multifunctional fibers, optical waveguides, light-emitting diodes, upconversion nanoparticles, optical neuromodulation based on the secondary effects of light, and unconventional light sources facilitated by ultrasound and magnetic fields. We conclude our review with an outlook on new methods and mechanisms that afford optical neuromodulation with minimal invasiveness and footprint.
(© The Author(s) 2022. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd.)
Databáze: MEDLINE
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