Effectiveness of nitrous oxide sedation for otolaryngologic examination in the outpatient clinic in uncooperative children.

Autor: Brathen E; Department of Urology, Antwerp University Hospital, Belgium., Boudewyns A; Department of Otorhinolaryngology, Antwerp University Hospital, Belgium; Faculty of Medicine and Translational Neurosciences, University of Antwerp, Belgium., Verhulst S; Department of Paediatrics, Antwerp University Hospital, Belgium; Lab of Experimental Medicine and Pediatrics, University of Antwerp, Belgium., Roete A; Department of Paediatrics, Antwerp University Hospital, Belgium., Verlooy J; Department of Paediatrics, Antwerp University Hospital, Belgium., van Meerbeeck N; Department of Paediatrics, Antwerp University Hospital, Belgium., Vanderveken O; Department of Otorhinolaryngology, Antwerp University Hospital, Belgium; Faculty of Medicine and Translational Neurosciences, University of Antwerp, Belgium., van der Poel N; Department of Otorhinolaryngology, Antwerp University Hospital, Belgium; Faculty of Medicine and Translational Neurosciences, University of Antwerp, Belgium. Electronic address: Nicolien.vanderpoel@uza.be.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2022 Nov; Vol. 162, pp. 111328. Date of Electronic Publication: 2022 Sep 28.
DOI: 10.1016/j.ijporl.2022.111328
Abstrakt: Objectives: The aim of this study is to investigate the efficacy of equimolar mixture of 50% nitrous oxide and oxygen (EMONO) to obtain conscious sedation for otolaryngologic examinations and minor Ear-Nose-Throat (ENT) procedures in children with or without comorbidities.
Methods: Retrospective analysis of patient records from all children who were uncooperative during routine ENT examination, and therefore underwent otomicroscopic examinations and/or minor ENT procedures sedated with EMONO in the outpatient ENT clinic. The following data were collected: patients characteristics, sedative effect, analgesic effect and adverse effects. Patients were divided into three subgroups: 1) no relevant comorbidities, 2) Down Syndrome and 3) other causes of behavioural problems or developmental delay.
Results: Data were analyzed for 99 patients (170 procedures). Seven procedures failed. A good to excellent sedative and analgesic effect was obtained in most patients without a difference between subgroups. Minor and transient side effects were encountered in one third (34%) of the patients.
Conclusions: EMONO is an effective agent to achieve conscious sedation and to perform ENT examinations or minor procedures in otherwise uncooperative children with or without developmental delay.
Competing Interests: Declaration of competing interest The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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