A starch-rich treat affects enteroinsular responses in ponies.

Autor:	Sibthorpe PEM; School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia., Fitzgerald DM; School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia., Chen L; Central Analytical Research Facility, Queensland University of Technology, Brisbane, QLD, Australia., Sillence MN; School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia., de Laat MA; School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD, Australia.
Jazyk:	angličtina
Zdroj:	Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2022 Oct 06; Vol. 260 (S3), pp. S94-S101. Date of Electronic Publication: 2022 Oct 06.
DOI:	10.2460/javma.22.06.0272
Abstrakt:	Objective: To determine the effect of a starch-rich treat, added to the daily diet of ponies for 10 days, on enteroinsular responses to meal consumption. Animals: 10 mixed-breed adult ponies owned by Queensland University of Technology were used in the study. Six ponies were metabolically healthy, and 4 were insulin dysregulated at the start of the study, according to the results of an in-feed oral glucose test. Procedures: A bread-based treat was offered twice daily for 10 days, adding 0.36 ± 0.04 g/kg body weight (BW) carbohydrates to the daily diet. Before and after treatment, the intestinal capacity for simple carbohydrate absorption was approximated with a modified D-xylose absorption test. Plasma glucagon-like peptide-2 (GLP-2), blood glucose, and serum insulin responses to eating were also measured before and after treatment. Results: The absorption of D-xylose (area under the curve [AUC]) increased 1.6-fold (P < .001) after 10 days of eating the treat. In addition, while basal (fasted) GLP-2 concentrations were not affected, GLP-2 AUC increased 1.4-fold in response to eating (P = .005). The treat did not change blood glucose or serum insulin concentrations, before, during, or after eating. Clinical Relevance: A small amount of additional carbohydrate each day in the form of a treat can cause a measurable change in the enteroinsular responses to eating.
Databáze:	MEDLINE
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