Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas).

Autor:	Dos Santos E; Postgraduate Program on Health and Environment, University of the Region of Joinville-Univille, Joinville, Brazil., Wollmann GM; Department of Medicine, University of the Region of Joinville-Univille, Joinville, Brazil., Nagel V; Joinville Stroke Registry, Hospital Municipal São José, Joinville, Brazil., Ponte HMS; Department of Nursing, Inta University Center-UNINTA, Sobral, Brazil., Furtado LETA; Department of Clinical Medicine, Federal University of Ceará, Sobral, Brazil., Martins-Filho RKV; Hospital das Clínicas de Ribeirão Preto, University of São Paulo-USP, Ribeirão Preto, Brazil., Weiss G; Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.; Hospital Moinhos de Vento, Porto Alegre, Brazil., Martins SCO; Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.; Hospital Moinhos de Vento, Porto Alegre, Brazil., Ferreira LE; Postgraduate Program on Health and Environment, University of the Region of Joinville-Univille, Joinville, Brazil.; Department of Medicine, University of the Region of Joinville-Univille, Joinville, Brazil., de França PHC; Postgraduate Program on Health and Environment, University of the Region of Joinville-Univille, Joinville, Brazil.; Department of Medicine, University of the Region of Joinville-Univille, Joinville, Brazil., Cabral NL; Postgraduate Program on Health and Environment, University of the Region of Joinville-Univille, Joinville, Brazil.; Department of Medicine, University of the Region of Joinville-Univille, Joinville, Brazil.; Joinville Stroke Registry, Hospital Municipal São José, Joinville, Brazil.
Jazyk:	angličtina
Zdroj:	Frontiers in neurology [Front Neurol] 2022 Sep 15; Vol. 13, pp. 966785. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).
DOI:	10.3389/fneur.2022.966785
Abstrakt:	Background: Stroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood. Objective: The aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days post-stroke in the cities of different Brazilian macro-regions. Methods: This is an observational, prospective, and population-based study, led in Canoas (South), Joinville (South, reference center), Sertãozinho (Southeast), and Sobral (Northeast) in Brazil. It was developed according to the three-step criteria recommended by the World Health Organization to conduct population-based studies on stroke. Using different sources, all hospitalized and ambulatory patients with stroke were identified and the same criteria were kept in all cities. All first events were included, regardless of sex, age, or type of stroke. Demographic and risk factor data were collected, followed by biochemical, electrocardiographic, and radiological test results. Functional status and lethality were obtained using the mRankin scale through telephonic interview (validated Brazilian version). Results: In 1 year, 932 stroke cases were registered (784 ischemic stroke, 105 hemorrhagic stroke, and 43 subarachnoid hemorrhage). The incidence rates per 100,000 inhabitants, adjusted for the world population, were 63 in Canoas, 106 in Joinville, 72 in Sertãozinho, and 96 in Sobral. The majority (70.8%) were followed for 90 days. Kaplan-Meier curves showed that 90-day survival was different among cities. Sobral, which has the lowest socioeconomic indexes, revealed the worst results in terms of lethality and functional status. Conclusion: This study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer CS declared a shared affiliation with the author RM-F to the handling editor at the time of review. (Copyright © 2022 Santos, Wollmann, Nagel, Ponte, Furtado, Martins-Filho, Weiss, Martins, Ferreira, França and Cabral.)
Databáze:	MEDLINE
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