Adrenal crisis during pregnancy: Case report and obstetric perspective.

Autor: Gardella B; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.; Department Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Gritti A; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.; Department Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Scatigno AL; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.; Department Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Gallotti AMC; Institute of Radiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Perotti F; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.; Department Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Dominoni M; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.; Department Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Jazyk: angličtina
Zdroj: Frontiers in medicine [Front Med (Lausanne)] 2022 Sep 14; Vol. 9, pp. 891101. Date of Electronic Publication: 2022 Sep 14 (Print Publication: 2022).
DOI: 10.3389/fmed.2022.891101
Abstrakt: Adrenal dysfunction (AD) and, in particular, adrenal crisis are uncommon events in pregnant women, but associated with significant maternal and fetal morbidity and mortality if untreated or undiagnosed. Adrenal crisis may be confused with the common symptoms of pregnancy: the obstetricians should be able to promptly diagnose and treat it in order to avoid the adverse outcomes regarding the mother and the fetus. For this reason, AD must be treated by an expert multidisciplinary team. We presented a case report of a young pregnant woman with adrenal crisis due to tuberculosis, cocaine abuse, and massive bilateral hemorrhage with symptoms of emesis, hypotension, sudden abdominal pain, and leukocytosis. The most common issues of diagnosis and treatment are discussed and analyzed. Finally, we performed a review of the literature regarding adrenal crisis and adrenal insufficiency (AI) in pregnancy in order to clarify the management of these diseases in obstetrics setting.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Gardella, Gritti, Scatigno, Gallotti, Perotti and Dominoni.)
Databáze: MEDLINE