Quality of life improvement in patients with bone metastases undergoing palliative radiotherapy.

Autor:	Cañón V; Department of Radiation Oncology, Hospital Universitario Marqués de Valdecilla Santander, Spain., Gómez-Iturriaga A; Department of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Casquero F; Department of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Rades D; Department of Radiation Oncology, University of Lübeck, Lübeck, Germany., Navarro A; Department of Radiation Oncology, Instituto Catalán de Oncología, Barcelona, Spain., Del Hoyo O; Department of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Morillo V; Department of Radiation Oncology, Hospital de Castellón, Castellón, Spain., Willisch P; Department of Radiation Oncology, Hospital Meixoeiro, Vigo, Spain., López-Guerra JL; Department of Radiation Oncology, Hospital Virgen del Rocío, Sevilla, Spain., Illescas-Vacas A; Department of Radiation Oncology, Hospital Virgen Macarena, Sevilla, Spain., Ciervide R; Department of Radiation Oncology, Hospital San Chinarro, Madrid, Spain., Martinez-Indart L; Bioinformatics and Statistics Department, Hospital Universitario Cruces/Biocruces Heatlh Research, Barakaldo, Spain., Cacicedo J; Department of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Jazyk:	angličtina
Zdroj:	Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology [Rep Pract Oncol Radiother] 2022 Jul 29; Vol. 27 (3), pp. 428-439. Date of Electronic Publication: 2022 Jul 29 (Print Publication: 2022).
DOI:	10.5603/RPOR.a2022.0048
Abstrakt:	Background: The aim of the study was to analyze the impact of palliative radiotherapy on quality of life (QoL) in patients with symptomatic bone metastases. Materials and Methods: We present the results from a prospective multicentric study including 128 patients who provided pre- and post-radiotherapy (one month after treatment) brief pain inventory (BPI) assessments. Worst pain was recorded using the BPI (range: 0-10). Pain response was described according to the International Bone Metastases Consensus on palliative radiation. Regarding QoL, for each pre- and post-radiation BPI-questionnaire, scores from the interference domains were summed and averaged to obtain an overall interference score. Results: There was a significant correlation between radiation treatment response and improvement in all functional interference domains except sleeping. Patients > 75 years old presented a significantly higher improvement in general activity, mood and relationships with others compared to patients ≤ 75 years old. Patients presenting a baseline pain score ≥ 8 showed a higher improvement in the general activity item (p = 0.049). There was no statistically significant association between pretreatment ECOG, chemotherapy, primary tumor location and radiation schedule with any of the functional interference items. Conclusions: Patients who report pain relief after palliative radiotherapy also present a better quality of life including physical and psychosocial aspects. Competing Interests: Conflict of interests The authors declare that they have no competing interests. (© 2022 Greater Poland Cancer Centre.)
Databáze:	MEDLINE
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