Sex Differences in Psychiatric Comorbidities in Adolescents With Autism Spectrum Disorder: A National Inpatient Sample Analysis.
| Autor: | Vadukapuram R; Department of Psychiatry, The University of Texas Rio Grande Valley, Harlingen, Texas., Elshokiry AB; Department of Child and Adolescent Psychiatry, University of South Florida, Tampa, Florida.; Corresponding author: Amir Bishay Elshokiry, MD, MA, Department of Child and Adolescent Psychiatry, University of South Florida, 3515 E Fletcher Ave, Tampa, FL 33613 (amirbishay79@gmail.com)., Trivedi C; Texas Tech University Health Science Center at Permian Basin, Midland, Texas., Abouelnasr A; University of Virginia, Charlottesville, Virginia., Bataineh A; Jordan University of Science and Technology, Aydun, Irbid, Jordan., Usmani S; Dow University of Health Sciences, Karachi, Pakistan., Rodrigues SP; Mount Douglas Medical Clinic, British Columbia, Canada., Mansuri Z; Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts., Jain SB; Texas Tech University Health Science Center at Permian Basin, Midland, Texas. |
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| Jazyk: | angličtina |
| Zdroj: | The primary care companion for CNS disorders [Prim Care Companion CNS Disord] 2022 Sep 27; Vol. 24 (5). Date of Electronic Publication: 2022 Sep 27. |
| DOI: | 10.4088/PCC.21m03189 |
| Abstrakt: | Objective: To investigate sex differences in psychiatric comorbidities in adolescents with autism spectrum disorder (ASD). Methods: The US National Inpatient Sample dataset (January 2016 to December 2018) was used for this retrospective study. The patient population was selected by performing a query on all adolescent patients (aged 12-17 years) having ASD with the ICD-10-CM code starting with F84. All missing sex data were excluded. Additional data on mood disorders, anxiety disorders, personality disorders, adjustment disorders, psychotic disorders, attention-deficit/hyperactivity disorder (ADHD)/conduct disorders, sleep-wake disorders, and substance use disorders were collected. Data on psychiatric comorbidities were collected using the ICD-10-CM code provided in the Clinical Classifications Software of the dataset. Results: Mood disorders (37.4% vs 44.1%, P < .001) and anxiety disorders (29.4% vs 37.0%, P < .001) were more prevalent in females compared to males. The prevalence of ADHD and other conduct disorders was significantly higher in males than females (47.7% vs 36.7%, P < .001). Substance use disorders were slightly higher among males compared to females (3.7% vs 3.0%, P = .04). Conclusion: The study findings revealed statistically significant disparities in psychiatric comorbidities among adolescent male and female patients with ASD. These findings could serve as a pilot for larger-scale research with this patient population in the future. (© Copyright 2022 Physicians Postgraduate Press, Inc.) |
| Databáze: | MEDLINE |
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