Orientation pinwheels in primary visual cortex of a highly visual marsupial.

Autor:	Jung YJ; National Vision Research Institute, Melbourne, VIC, Australia., Almasi A; Optalert Limited, Melbourne, VIC, Australia., Sun SH; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Yunzab M; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Cloherty SL; School of Engineering, RMIT University, Melbourne, VIC, Australia., Bauquier SH; Veterinary Hospital, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, VIC, Australia., Renfree M; School of BioSciences, The University of Melbourne, Melbourne, VIC, Australia., Meffin H; Department of Biomedical Engineering, The University of Melbourne, Melbourne, VIC, Australia., Ibbotson MR; National Vision Research Institute, Melbourne, VIC, Australia.; Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Jazyk:	angličtina
Zdroj:	Science advances [Sci Adv] 2022 Sep 30; Vol. 8 (39), pp. eabn0954. Date of Electronic Publication: 2022 Sep 30.
DOI:	10.1126/sciadv.abn0954
Abstrakt:	Primary visual cortices in many mammalian species exhibit modular and periodic orientation preference maps arranged in pinwheel-like layouts. The role of inherited traits as opposed to environmental influences in determining this organization remains unclear. Here, we characterize the cortical organization of an Australian marsupial, revealing pinwheel organization resembling that of eutherian carnivores and primates but distinctly different from the simpler salt-and-pepper arrangement of eutherian rodents and rabbits. The divergence of marsupials from eutherians 160 million years ago and the later emergence of rodents and rabbits suggest that the salt-and-pepper structure is not the primitive ancestral form. Rather, the genetic code that enables complex pinwheel formation is likely widespread, perhaps extending back to the common therian ancestors of modern mammals.
Databáze:	MEDLINE
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