Isometric handgrip exercise impacts only on very short-term blood pressure variability, but not on short-term blood pressure variability in hypertensive individuals: A randomized controlled trial.

Autor:	Bertoletti OA; Programa de Pós-Graduação em Epidemiologia, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Ferrari R; Programa de Pós-Graduação em Cardiologia, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Ferlin EL; Serviço de Pesquisa Clínica, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Barcellos OM; Coordenadoria de Gestão da Tecnologia da Informação e Comunicação, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Fuchs SC; Programa de Pós-Graduação em Epidemiologia, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Programa de Pós-Graduação em Cardiologia, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Jazyk:	angličtina
Zdroj:	Frontiers in physiology [Front Physiol] 2022 Sep 13; Vol. 13, pp. 962125. Date of Electronic Publication: 2022 Sep 13 (Print Publication: 2022).
DOI:	10.3389/fphys.2022.962125
Abstrakt:	Background: The effect of a single isometric handgrip exercise (IHG) on blood pressure (BP) variability (BPV) has not been addressed. This randomized controlled trial evaluated the effect of IHG vs. sham on BPV and BP. Methods: Hypertensive patients using up to two BP-lowering medications were randomly assigned to IHG (4 × 2 min; 30% of maximal voluntary contraction, MVC, with 1 min rest between sets, unilateral) or sham (protocol; 0.3% of MVC). Systolic and diastolic BP were assessed beat-to-beat in the laboratory before, during, and post-intervention and also using 24-h ambulatory BP monitoring (ABPM). BPV was expressed as average real variability (ARV) and standard deviation (SD). Results: Laboratory BPV, ARV and SD variability, had marked increase during the intervention, but not in the sham group, decreasing in the post-intervention recovery period. The overall change in ARV from pre- to 15 min post-intervention were 0.27 ± 0.07 (IHG) vs. 0.05 ± 0.15 (sham group), with a statistically significant p -value for interaction. Similarly, mean systolic BP increased during the intervention (IHG 165.4 ± 4.5 vs. sham 152.4 ± 3.5 mmHg; p = 0.02) as did diastolic BP (104.0 ± 2.5 vs. 90.5 ± 1.7 mmHg, respectively; p < 0.001) and decreased afterward. However, neither the short-term BPV nor BP assessed by ABPM reached statistically significant differences between groups. Conclusion: A single session of IHG reduces very short-term variability but does not affect short-term variability. IHG promotes PEH in the laboratory, but does not sustain 24-h systolic and diastolic PEH beyond the recovery period. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Bertoletti, Ferrari, Ferlin, Barcellos and Fuchs.)
Databáze:	MEDLINE
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