What do we have that is new in antifungal peptides? A patent review.

Autor: Zambrano P; Departamento de Farmacia. Universidad Nacional de Colombia, Bogotá, Colombia., Xavier LC; Faculty of Pharmacy, Federal University of Bahia, Salvador-BA, Brazil., Santos AM; Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Rossato L; Faculty of Health Sciences, Federal University of Grande Dourados, Dourados-MS, Brazil., da Costa JC; Faculty of Pharmacy, Department of Pharmaceutical Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Serafini MR; Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Aragón M; Departamento de Farmacia. Universidad Nacional de Colombia, Bogotá, Colombia., Souto RB; Faculty of Pharmacy, Federal University of Bahia, Salvador-BA, Brazil., Alves IA; Postgraduate Program in Pharmaceutical Sciences at the State University of Bahia, Salvador-BA, Brazil & Faculty of Pharmacy, Federal University of Bahia, Salvador-BA, Brazil.
Jazyk: angličtina
Zdroj: Future microbiology [Future Microbiol] 2022 Nov; Vol. 17, pp. 1421-1432. Date of Electronic Publication: 2022 Sep 28.
DOI: 10.2217/fmb-2022-0105
Abstrakt: Drugs used to fight fungal infections may cause toxic or adverse drug interactions. For this reason, there is an increase in the development of natural, semisynthetic and synthetic antifungal peptides. This study aimed to perform a patent review to identify the advances in peptides to treat fungal infections. In a preliminary assessment, 597 patents were identified from the database. Then, duplicated patents (62) and those with titles in disagreement with the scope of this review (196) were excluded. Then, six patents were not in English or Spanish. Following the screening, 288 patents were outside the focus of this review, according to their abstract and description. The final selection covered 45 patents.
Databáze: MEDLINE