Unprotected Left Main Revascularization in the Setting of Non-coronary Atherosclerosis: Gulf Left Main Registry.

Autor: Daoulah A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia. Electronic address: aminddaoulah@yahoo.com., Abozenah M; Department of Cardiovascular Medicine, University of Massachusetts Chan Medical School - Baystate Medical Center, Springfield, MA., Alshehri M; Department of Cardiology, Prince Khaled Bin Sultan Cardiac Center, Khamis Mushait, Kingdom of Saudi Arabia., Hersi AS; Department of Cardiac Sciences, King Fahad Cardiac Center, King Saud University, Riyadh, Kingdom of Saudi Arabia., Yousif N; Department of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, Awali, Kingdom of Bahrain., Garni TA; Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia., Abuelatta R; Department of Cardiology, Madinah Cardiac Center, Madinah, kingdom of Saudi Arabia., Almahmeed W; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, UAE., Alasmari A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia., Alzahrani B; Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia., Ghani MA; Department of Cardiology, Madinah Cardiac Center, Madinah, kingdom of Saudi Arabia., Amin H; Department of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, Awali, Kingdom of Bahrain., Hashmani S; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, UAE., Hiremath N; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, UAE., Alharbi AW; Department of of Internal Medicine, Gastroenterology Section, Gastroenterologist & Advanced Therapeutic Endoscopist, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia., Kazim HM; Department of Cardiology, Alhada Armed Forces Hospital, Taif, Kingdom of Saudi Arabia., Refaat W; Department of Cardiology, Prince Sultan Cardiac Center, Al Hassa, Kingdom of Saudi Arabia., Selim E; Department of Cardiology, Alhada Armed Forces Hospital, Taif, Kingdom of Saudi Arabia., Dahdouh Z; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia., Aithal J; Department of Cardiology, Yas Clinic, Khalifa City A, Abu Dhabi, UAE., Ibrahim AM; Department of Cardiology, Saudi German Hospital, Jeddah, Kingdom of Saudi Arabia., Elganady A; Department of Cardiology, Dr Erfan and Bagedo General Hospital, Jeddah, Kingdom of Saudi Arabia., Qutub MA; Cardiology Center of Excellence, Department of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Alama MN; Cardiology Center of Excellence, Department of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Abohasan A; Department of cardiology, Prince Sultan Cardiac Center, Qassim, Kingdom of Saudi Arabia., Hassan T; Department of Cardiology, Bugshan General Hospital, Jeddah, Kingdom of Saudi Arabia., Balghith M; King Abdulaziz Cardiac Center, College of Medicine, King Saud Bin Abdulaziz University for Health Science, Riyadh, kingdom of Saudi Arabia., Hussien AF; Department of cardiology, International Medical Center, Jeddah, Kingdom of Saudi Arabia., Abdulhabeeb IA; Department of Cardiology, king Abdulaziz Specialist Hospital, Al Jawf, Kingdom of Saudi Arabia., Ahmad O; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia., Ramadan M; Department of Cardiology, Prince Sultan Cardiac Center, Al Hassa, Kingdom of Saudi Arabia., Alqahtani AH; Department of Emergency Medicine, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia., Ahmed FA; King Abdul Aziz Medical City, National Guard Health Affairs, Jeddah, Kingdom of Saudi Arabia., Qenawi W; Department of Cardiology, Prince Khaled Bin Sultan Cardiac Center, Khamis Mushait, Kingdom of Saudi Arabia., Shawky A; Department of Cardiology, Prince Khaled Bin Sultan Cardiac Center, Khamis Mushait, Kingdom of Saudi Arabia., Ghonim AA; Cardiology Center of Excellence, Department of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Jamjoom A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia., El-Sayed O; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia., Elmahrouk A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia; Department of Cardiothoracic Surgery, Tanta University, Tanta, Egypt., Elfarnawany A; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia., Elsheikh-Mohamed NE; Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia., Abumelha BK; Department of Family Medicine, King Abdulaziz Medical City, National Guard Hospital, Riyadh, Kingdom of Saudi Arabia., Shawky AM; Department of Cardiology, Dr Erfan and Bagedo General Hospital, Jeddah, Kingdom of Saudi Arabia., Arafat AA; Cardiothoracic Surgery Department, Faculty of Medicine, Tanta University, Egypt., Naser MJ; Department of Internal Medicine, University of Massachusetts Chan Medical School - Baystate, Springfield, Springfield, MA., Elmahrouk Y; Faculty of Medicine, Tanta University, Tanta, Egypt., Alhamid S; Department of Emergency Medicine, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia., Lotfi A; Department of Cardiovascular Medicine, University of Massachusetts Chan Medical School - Baystate Medical Center, Springfield, MA.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2023 Jan; Vol. 48 (1), pp. 101424. Date of Electronic Publication: 2022 Sep 24.
DOI: 10.1016/j.cpcardiol.2022.101424
Abstrakt: Coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in revascularization of left main coronary artery (LMCA) disease has been evaluated in previous studies. However, there has been minimal study of the relationship between co-existing non-coronary atherosclerosis (NCA) and LMCA disease revascularization. We aim to examine this relationship. The Gulf-LM study is a retrospective analysis of unprotected LMCA revascularization cases undergoing PCI with second generation drug-eluting stent vs CABG across 14 centers within 3 Gulf countries between January 2015 and December 2019. A total of 2138 patients were included, 381 with coexisting NCA and 1757 without. Outcomes examined included major adverse cardiovascular and cerebrovascular events (MACCE), cardiac and non-cardiac death, and all bleeding. In patients with NCA, preexisting myocardial infarction and congestive heart failure were more common, with PCI being the most common revascularization strategy. A statistically significant reduction in in-hospital MACCE and all bleeding was noted in patients with NCA undergoing PCI as compared to CABG. At a median follow-up of 15 months, MACCE and major bleeding outcomes continued to favor the PCI group, though no such difference was identified between revascularization strategies in patients without NCA.In this multicenter retrospective study of patients with and without NCA who require revascularization (PCI and CABG) for unprotected LMCA disease, PCI demonstrated a better clinical outcome in MACCE both in-hospital and during the short-term follow-up in patients with NCA. However, no such difference was observed in patients without NCA.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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