Gut Microbiota Interventions for the Management of Obesity: A Literature Review.

Autor: Gill VJS; Internal Medicine, Baylor College of Medicine, Houston, USA., Soni S; Medicine, Punjab Institute of Medical Sciences, Jalandhar, IND.; Public Health, University of Texas Health Science Center at Houston, Houston, USA., Shringarpure M; Medicine, The Institute of Liver and Biliary Sciences (ILBS), Delhi, IND., Anusheel; General Practice, Shanti Gopal Hospital, Ghaziabad, IND., Bhardwaj S; Medicine, Kathmandu University School of Medical Sciences, Kathmandu, NPL., Yadav NK; Medicine, Nepalgunj Medical College, Kathmandu, NPL., Patel A; Internal Medicine, Spartan Health Science University School of Medicine, Vieux Fort, LCA., Patel A; Internal Medicine, Spartan Health Science University School of Medicine, Vieux Fort, LCA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2022 Sep 19; Vol. 14 (9), pp. e29317. Date of Electronic Publication: 2022 Sep 19 (Print Publication: 2022).
DOI: 10.7759/cureus.29317
Abstrakt: The gut microbiota (GM) has been recognized as an important factor in the development of metabolic diseases such as obesity; it has been reported that the composition of the GM differs in obese and lean subjects, suggesting that microbiota dysbiosis can contribute to changes in body weight. Dysbiosis occurs due to an imbalance in the composition of gut bacteria, changes in the metabolic process, or changes in the distribution of microbiota within the gut. Dysbiosis can change the functioning of the intestinal barrier and the gut-associated lymphoid tissues (GALT). Microbial manipulation may help with preventing or treating weight gain and associated comorbidities. Approaches to this may range from dietary manipulation, which is suitable to treat the individual's microflora, to probiotics, prebiotics, synbiotics, and fecal microbiota transplant (FMT).
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Gill et al.)
Databáze: MEDLINE
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