inPhocus: Current State and Challenges of Phage Research in Singapore.

Autor:	Verma NK; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore.; Singapore Eye Research Institute, Singapore., Tan SJ; Institute for Health Technologies, Nanyang Technological University Singapore, Singapore., Chen J; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chen H; Computational and Systems Biology, Genome Institute of Singapore, Singapore., Ismail MH; Singapore Centre for Environmental Life Sciences Engineering, Microbial Biofilms Cluster, Nanyang Technological University Singapore, Singapore., Rice SA; Singapore Centre for Environmental Life Sciences Engineering, Microbial Biofilms Cluster, Nanyang Technological University Singapore, Singapore.; Microbiomes for One Systems Health and Agriculture and Food, Westmead NSW, CSIRO, Australia., Bifani P; Yong Loo Lin School of Medicine, National University of Singapore, ASTAR Infectious Diseases Labs, Singapore and the London School of Hygiene and Tropical Medicine, London, United Kingdom., Hariharan S; Gangagen Biotechnologies Private Ltd., Bangalore, India., Paul VD; Gangagen Biotechnologies Private Ltd., Bangalore, India., Sriram B; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore., Dam LC; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore., Chan CC; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore., Ho P; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore., Goh BC; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore., Chung SJ; Department of Infectious Diseases, Singapore General Hospital, Singapore.; Singhealth Duke-NUS Medicine Academic Clinical Programme, Singapore., Goh KCM; Department of Microbiology, Singapore General Hospital, Singapore., Thong SH; Department of Pharmacy, Singapore General Hospital, Singapore., Kwa AL; Singhealth Duke-NUS Medicine Academic Clinical Programme, Singapore.; Department of Pharmacy, Singapore General Hospital, Singapore.; Emerging Infectious Diseases, Duke-NUS Medical School, Singapore., Ostrowski A; Cellexus International Ltd., Dundee, United Kingdom., Aung TT; Department of Microbiology and Immunology, Immunology Translational Research Program and Centre for Life Science, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Razali H; Asian School of the Environment, Nanyang Technological University Singapore, Singapore., Low SWY; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore., Bhattacharyya MS; CSIR-Institute of Microbial Technology, Chandigarh, India., Gautam HK; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Lakshminarayanan R; Singapore Eye Research Institute, Singapore., Sicheritz-Pontén T; Center for Evolutionary Hologenomics, The GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Clokie MRJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom., Moreira W; Department of Microbiology and Immunology, Immunology Translational Research Program and Centre for Life Science, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., van Steensel MAM; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore.
Jazyk:	angličtina
Zdroj:	PHAGE (New Rochelle, N.Y.) [Phage (New Rochelle)] 2022 Mar 01; Vol. 3 (1), pp. 6-11. Date of Electronic Publication: 2022 Mar 18.
DOI:	10.1089/phage.2022.29028.nkv
Abstrakt:	Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore (NTU) and Yong Loo Lin School of Medicine, National University of Singapore (NUS) recently co-organized a virtual symposium on Bacteriophage and Bacteriophage-Derived Technologies, which was attended by more than 80 participants. Topics were discussed relating to phage life cycles, diversity, the roles of phages in biofilms and the human gut microbiome, engineered phage lysins to combat polymicrobial infections in wounds, and the challenges and prospects of clinical phage therapy. This perspective summarizes major points discussed during the symposium and new perceptions that emerged after the panel discussion. Competing Interests: No competing financial interests exist. (Copyright 2022, Mary Ann Liebert, Inc., publishers.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu