Laparoscopic transgastric resection of a gastric leiomyosarcoma: report of a rare case.

Autor: Panzardi N; General Surgery Department, Hospital Británico de Buenos Aires, Perdriel 74, C1280 AEB Buenos Aires, Argentina.; https://orcid.org/0000-0002-1092-1132., Mihura-Irribarra M; Esophageal and Gastric Surgery Department, Hospital Británico de Buenos Aires, Perdriel 74, C1280 AEB Buenos Aires, Argentina.; https://orcid.org/0000-0001-7131-7951., Speisky D; Pathology Department, Hospital Británico de Buenos Aires,Perdriel 74, C1280 AEB Buenos Aires, Argentina.; https://orcid.org/0000-0002-5237-8924., Fernandez-Alberti J; General Surgery Department, Hospital Británico de Buenos Aires, Perdriel 74, C1280 AEB Buenos Aires, Argentina.; https://orcid.org/0000-0002-1827-7361., Pasquini MT; General Surgery Department, Hospital Británico de Buenos Aires, Perdriel 74, C1280 AEB Buenos Aires, Argentina., Dezanzo P; Pathology Department, Hospital Británico de Buenos Aires,Perdriel 74, C1280 AEB Buenos Aires, Argentina.; https://orcid.org/0000-0001-9893-2487., Pirchi DE; General Surgery Department, Hospital Británico de Buenos Aires, Perdriel 74, C1280 AEB Buenos Aires, Argentina.; https://orcid.org/0000-0002-7353-0470.
Jazyk: angličtina
Zdroj: Ecancermedicalscience [Ecancermedicalscience] 2022 Jul 04; Vol. 16, pp. 1419. Date of Electronic Publication: 2022 Jul 04 (Print Publication: 2022).
DOI: 10.3332/ecancer.2022.1419
Abstrakt: Gastric leiomyosarcoma is a rare type of tumour that is far less prevalent than gastrointestinal stromal tumours. We describe a case of a 42-year-old male patient who consulted for upper abdominal pain. Blood work revealed low haemoglobin levels, requiring red blood cell transfusions. An esophagogastroduodenoscopy was performed, showing a submucosal tumour with central ulceration in the greater gastric curvature. The patient underwent an endoscopic ultrasound with fine needle biopsy and the sample showed a spindle cell neoplasia. Computed tomography scan demonstrated absence of distant metastases. Upon multidisciplinary consensus, it was decided to perform surgery. A laparoscopic approach was conducted, where no peritoneal lesions were observed. Transgastric resection of the tumour was performed. Free tumour margins were achieved following oncologic criteria (minimum tumour manipulation and one-piece resection without damaging the tumour capsule). After exhaustive sampling, the final pathology report informed an 11 × 9 × 5 cm gastric leiomyosarcoma. Immunohistochemical examination showed positivity with smooth muscle actin, muscle-specific actin, calponin and desmin. The patient had an uneventful recovery, and 6 post-operative months' clinical, tomographic and endoscopic control informed no disease recurrence. To the best of our knowledge, there are less than 20 published cases of patients with diagnosis of gastric leiomyosarcoma. This study highlights the importance of reporting this entity, in order to contribute to the available literature concerning this topic.
Competing Interests: None.
(© the authors; licensee ecancermedicalscience.)
Databáze: MEDLINE
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