Intraparenchymal Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report.

Autor: Laghaei Farimani P; Medicine, University of British Columbia, Vancouver, CAN.; Neurosurgery, Vancouver General Hospital, Vancouver, CAN., Karthikeyan V; Neurosurgery, University of Toronto, Toronto, CAN., Fatehi M; Neurosurgery, Vancouver General Hospital, Vancouver, CAN., Levine A; Pathology and Laboratory Medicine, Vancouver General Hospital, Vancouver, CAN., Slack GW; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, CAN., Mackenzie IR; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, CAN., Haw C; Neurosurgery, Vancouver General Hospital, Vancouver, CAN.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2022 Aug 23; Vol. 14 (8), pp. e28301. Date of Electronic Publication: 2022 Aug 23 (Print Publication: 2022).
DOI: 10.7759/cureus.28301
Abstrakt: Marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (MALT) type, which is primary to the central nervous system (CNS), is a rare lesion, with those originating within the parenchyma even more so. We present the case of a 64-year-old male with weakness in the left hand and focal motor seizures of his arm, who was found to have a right frontal intraparenchymal lesion. Following resection, histopathological and immunohistochemical evaluations were completed, leading to a diagnosis of a primary CNS MZBCL of MALT type in the context of a negative workup of systemic disease. Neuroimaging, histopathological, and immunohistochemical findings, as well as a comprehensive literature review of similar cases, are discussed.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Laghaei Farimani et al.)
Databáze: MEDLINE