One-stage revision arthroplasty in a patient with ochronotic arthropathy accompanied by joint infection: A case report.

Autor: Wang XC; The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China., Zhang XM; Department of Orthopaedics, Xi'an International Medical Center Hospital, Xi'an 710100, Shaanxi Province, China., Cai WL; Department of Surgery, Baoji Hospital of Traditional Chinese Medicine, Baoji 721000, Shaanxi Province, China., Li Z; The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China., Ma C; The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China., Liu YH; Department of Orthopaedics, Xi'an International Medical Center Hospital, Xi'an 710100, Shaanxi Province, China., He QL; Department of Orthopaedics, Xi'an International Medical Center Hospital, Xi'an 710100, Shaanxi Province, China., Yan TS; Department of Orthopaedics, Xi'an International Medical Center Hospital, Xi'an 710100, Shaanxi Province, China., Cao XW; Department of Orthopaedic Surgery, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong Province, China. wscxw123@163.com.
Jazyk: angličtina
Zdroj: World journal of clinical cases [World J Clin Cases] 2022 Sep 06; Vol. 10 (25), pp. 9036-9043.
DOI: 10.12998/wjcc.v10.i25.9036
Abstrakt: Background: Ochronotic arthropathy (OcA) is a rare disease, which is caused by the accumulation of homogentisic acid in the joint. Patients with OcA have obvious joint pain and the disease progresses rapidly, eventually resulting in disability. Arthroplasty is an efficacious treatment in patients with OcA. However, when OcA patients have joint infection, is joint replacement an option? In the present report, we performed total knee arthroplasty in a patient with OcA and knee infection under the guidance of one-stage revision theory.
Case Summary: A 64-year-old male was referred to our hospital due to severe left knee pain with limited mobility for 2 years. On physical examination, the patient was found to have dark brown pigmentation of the sclera and auricle. Laboratory test results showed elevations in C-reactive protein level (65.79 mg/L) and erythrocyte sedimentation rate (90.00 mm/h). The patient underwent debridement of the left knee joint, during which the cartilage surface of the knee joint was found to be black-brown in color. Bacterial culture of synovial fluid revealed Achromobacter xylosoxidans . We then carried out arthroplasty under the guidance of the theory of one-stage revision. After surgery, the patient's left knee joint pain disappeared and function recovered without joint infection.
Conclusion: OcA accompanied by joint infection is rare. One-stage revision arthroplasty may be a treatment option for this disease.
Competing Interests: Conflict-of-interest statement: The authors have no conflicts of interest to declare.
(©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze: MEDLINE