Chlorine poisoning caused by improper mixing of household disinfectants during the COVID-19 pandemic: Case series.

Autor:	Lin GD; Department of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou 510010, Guangdong Province, China.; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China., Wu JY; Department of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou 510010, Guangdong Province, China., Peng XB; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China., Lu XX; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China., Liu ZY; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China., Pan ZG; Department of Critical Care Medicine, General Hospital of Southern Theater Command of PLA, Guangzhou 510010, Guangdong Province, China., Qiu ZW; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China., Dong JG; Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China. 347800520@qq.com.
Jazyk:	angličtina
Zdroj:	World journal of clinical cases [World J Clin Cases] 2022 Sep 06; Vol. 10 (25), pp. 8872-8879.
DOI:	10.12998/wjcc.v10.i25.8872
Abstrakt:	Background: Misuse of disinfectants during the coronavirus disease 2019 pandemic has led to several poisoning incidents. However, there are few clinical case reports on poisoning caused by improper mixing of household disinfectants. Aim: To summarize the clinical characteristics and treatment effects of chlorine poisoning caused by improper mixing of hypochlorite bleach with acidic cleaning agents. METHODSWe retrospectively analyzed baseline and clinical data, clinical symptoms, and treatment methods of seven patients with chlorine poisoning who were admitted to the National Army Poisoning Treatment Center. Results: Among the seven patients, the average poisoning time (exposure to admission) was 57 h (4-240 h). All patients were involved in cleaning bathrooms. Chest computed tomography scans revealed bilateral lung effusions or inflammatory changes in five patients. The partial pressure of oxygen decreased in six patients, and respiratory failure occurred in one. Five patients had different degrees of increase in white blood cell count. Humidified oxygen therapy, non-invasive mechanical ventilation, anti-inflammatory corticosteroids, antioxidants, and antibiotics were administered for treatment. The average length of hospital stay was 7 d (4-9 d). All seven patients recovered and were discharged. Conclusion: Improper mixing of household disinfectants may cause damage to the respiratory system due to chlorine poisoning. Corticosteroids may improve lung exudation in severe cases, and symptomatic supportive treatment should be performed early. Competing Interests: Conflict-of-interest statement: All authors declare that they have no competing interests. (©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze:	MEDLINE
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