[18F-fluorodesoxyglucose positron emission tomography/computed tomography in extramedullary multiple myeloma].

Autor:	Lissarrague E; Universidad de la República, Montevideo, Uruguay., Fregeiro MS; Universidad de la República, Montevideo, Uruguay., Binstok Y; Universidad de la República, Montevideo, Uruguay., Barla C; Universidad de la República, Montevideo, Uruguay., Cavani M; Universidad de la República, Montevideo, Uruguay., Frachia F; Universidad de la República, Montevideo, Uruguay., Ranero S; Hospital de Clínicas Dr. Manuel Quíntela, Universidad de la República, Montevideo, Uruguay., Servente L; Departamento Clínico de Imagenología, Hospital de Clínicas Dr. Manuel Quintela, Universidad de la República, Montevideo, Uruguay., Riva E; Hospital de Clínicas Dr. Manuel Quíntela, Universidad de la República, Montevideo, Uruguay.
Jazyk:	Spanish; Castilian
Zdroj:	Revista medica de Chile [Rev Med Chil] 2022 Feb; Vol. 150 (2), pp. 199-205.
DOI:	10.4067/S0034-98872022000200199
Abstrakt:	Background: 18F-fluorodesoxyglucose positron emission tomography/ computed tomography (PET-CT) has a high sensitivity and specificity to detect medullary and extramedullary lesions in multiple myeloma (MM). Aim: To describe the findings of PET-CT in extramedullary multiple myeloma (EMM) at diagnosis and at relapse, and correlate its results with clinical variables, response to treatment and survival. Materials and Methods: Review of medical records and PET-CT reports of 39 patients with multiple myeloma (MM) who had at least one PET-CT study, treated between January 1, 2015, and January 1, 2019 at a clinical hospital. Results: The Standard Uptake Values for each hypermetabolic lesion were not described in PET-CT reports. Fifteen patients had an EMM and in eight, without a previous clinical suspicion, PET-TC lead to the diagnosis. The mortality rate in the 39 patients with MM was 46%. Sixty seven percent of deaths occurred in patients with EMM. Conclusions: PET-TC was useful to diagnose EMM. However, a standardization in PETCT reports would be required to unify criteria. As previously reported, EMM had a greater aggressiveness and lower survival.
Databáze:	MEDLINE
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