Investigating the psychometric properties of the EQ-5D-Y-3L, EQ-5D-Y-5L, CHU-9D, and PedsQL in children and adolescents with osteogenesis imperfecta.

Autor: Xu RH; Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China.; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China., Zhu L; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China., Sun R; The Illness Challenge Foundation, Beijing, China., Tan RL; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Luo N; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Zou S; Department of Intensive Care Unit, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. zousn@mail.sysu.edu.cn., Dong D; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China. dongdong@cuhk.edu.hk.
Jazyk: angličtina
Zdroj: European journal of pediatrics [Eur J Pediatr] 2022 Dec; Vol. 181 (12), pp. 4049-4058. Date of Electronic Publication: 2022 Sep 26.
DOI: 10.1007/s00431-022-04626-1
Abstrakt: The objective of this study was to evaluate and compare the psychometric properties of the EQ-5D-Y-3L, EQ-5D-Y-5L, CHU-9D, and PedsQL, in a sample of children and adolescents with osteogenesis imperfecta (OI). A web-based cross-sectional survey was conducted among Chinese children and adolescents with OI in 2021. The EQ-5D-Y-3L, EQ-5D-Y-5L, CHU-9D, and PedsQL were used to assess the health-related quality of life for the participants. Construct validity, including convergent and divergent validity, known-group validity, and test-retest reliability, was examined to assess the psychometric properties of the measures. A total of 157 pediatric OI patients self-completed the questionnaire. Few of them reported the full health status. A strong ceiling effect was observed for all dimensions on the EQ-5D-Y and most on CHU-9D. Most dimensions of the EQ-5D-Y and CHU-9D showed statistically significant correlations with the hypothesized PedsQL subscales. The test-retest reliability for the EQ-5D-Y-3L, EQ-5D-Y-5L, and CHU-9D was acceptable. The EQ-5D-Y-5L showed a better known-group validity than EQ-5D-Y-3L, CHU-9D, and PedsQL in differentiating patients in risk groups.
Conclusion: The results confirmed that the EQ-5D-Y and CHU-9D are reliable and valid in pediatric OI patients. The EQ-5D-Y-5L performed better than EQ-5D-Y-3L regarding acceptability, convergent validity, and discriminatory power.
What Is Known: • Performance of the preference-based measures has never been reported in patients with Osteogenesis imperfecta.
What Is New: • The EQ-5D-Y demonstrated higher sensitivity and discriminatory power than the CHU-9D in patients with osteogenesis Imperfecta • The EQ-5D-Y-3L performed slightly better than EQ-5D-Y-5L regarding convergent validity and discriminant ability.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje