Dietary weight loss intervention provides improvement of gastroesophageal reflux disease symptoms-A randomized clinical trial.

Autor: Valentini DF Jr; Medicine: Surgical Sciences, Medical School of Universidade Federal do Rio Grande do Sul (FAMED-UFRGS), Porto Alegre, Rio Grande do Sul, Brazil., Fernandes D; Gastroenterology and Hepatology, Medical School of Universidade Federal do Rio Grande do Sul (FAMED-UFRGS), Porto Alegre, Rio Grande do Sul, Brazil., Campos VJ; Medicine: Surgical Sciences, Medical School of Universidade Federal do Rio Grande do Sul (FAMED-UFRGS), Porto Alegre, Rio Grande do Sul, Brazil., Mazzini GS; Service of Digestive Surgery, Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil., Gurski RR; Medicine: Surgical Sciences, Medical School of Universidade Federal do Rio Grande do Sul (FAMED-UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.; Gastroenterology and Hepatology, Medical School of Universidade Federal do Rio Grande do Sul (FAMED-UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.; Service of Digestive Surgery, Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Jazyk: angličtina
Zdroj: Clinical obesity [Clin Obes] 2023 Feb; Vol. 13 (1), pp. e12556. Date of Electronic Publication: 2022 Sep 23.
DOI: 10.1111/cob.12556
Abstrakt: To evaluate the effect of dietary interventions aimed at weight loss in gastroesophageal reflux disease (GERD) symptoms and general health-related quality of life (HRQL) in overweight and obese patients. A population of GERD patients were randomized into two groups: the intervention group received individualized dietary counselling on scheduled appointments throughout 6 months of follow-up (n = 31) and the control group received only informative dietary guidelines on baseline (n = 31). Anthropometric data were monthly collected, and the HRQL score for GERD (GERD-HRQL) and the Health Survey (SF-36) questionnaires were applied on baseline and reevaluated at the end of follow-up. Dietary intervention led to an average weight loss of 4.4 kg (±5.3) and an average BMI reduction of 1.7 kg/m 2 (±2.9) compared to an increase in weight of 2.1 kg (±4.4) (p < .001) and an increase in BMI of 1.3 (±6.3) (p = 0.023) in the control group. Individuals in the intervention group had a mean decrease in symptoms of 6.8 (±5.5) points while the control group had worsening of their symptoms with an increase of 3.3 (±4) points (p < .001) in the disease-specific questionnaire. There was a positive association between weight loss and reduction of symptoms as measured by the GERD-HRQL score (r = .49; p < .001). Dietary intervention for 6 months with an individualized low-calorie diet program produces weight loss and a significant improvement in GERD-related symptoms, as well as in HRQL.
(© 2022 World Obesity Federation.)
Databáze: MEDLINE
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