Clinical pathology aspect on diagnosis cholelithiasis in β-Thalassemia patient: A case report.
| Autor: | Maulana MB; Study Program of Clinical Pathology, Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia., Fuadi MR; Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. |
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| Jazyk: | angličtina |
| Zdroj: | Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2022 Aug 24; Vol. 81, pp. 104454. Date of Electronic Publication: 2022 Aug 24 (Print Publication: 2022). |
| DOI: | 10.1016/j.amsu.2022.104454 |
| Abstrakt: | Background: Thalassemia is categorized based on the abnormal globin chain and is divided into primary, intermediate, and minor subtypes based on the chain abnormality, respectively. Case Presentation: An Indonesian adolescent, 18 years old, complained of abdominal pain for 1-day. Medical history patient showed thalassemia for 13 years, routine control and received transfusions. Physical examination: Anemic conjunctiva (+/+), epigastric tenderness (+). Laboratory tests: Hb of 4.2 g/dL, MCV of 59.8 fL, and MCH of 19.6 pg. Peripheral blood smears showed microcytic hypochromic, target cells, and teardrop cells. Increased albumin: creatinine ratio ≥300 mg/gr. Hb Electrophoresis showed increased HbF and HbA2 fractions. Abdominal Ultrasound showed cholelithiasis. The patient performed laparoscopic cholecystectomy and was successful. Discussion: Cholelithiasis is often found in thalassemia intermedia complications. Regular ultrasound examination in β-Thalassemia is used to detect cholelithiasis. Conclusion: Clinical pathology analysis supports the diagnosis of cholelithiasis in the β-Thalassemia patient. Competing Interests: Muhammad Bintang Maulana and Muhamad Robi'ul Fuadi declare that they have no conflict of interest. (© 2022 The Authors.) |
| Databáze: | MEDLINE |
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