Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch).

Autor:	Escalona M; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA., VanCampen J; Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR 97239, USA., Maurer NW; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA., Haukness M; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.; University of California Santa Cruz Genomics Institute, Santa Cruz, CA 95064, USA., Okhovat M; Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR 97239, USA., Harris RS; Department of Biology, Pennsylvania State University, University Park, PA, USA., Watwood A; Department of Biology, Pennsylvania State University, University Park, PA, USA., Hartley GA; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06296, USA.; Institute for Systems Genomics, University of Connecticut, Storrs, CT 06296, USA., O'Neill RJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06296, USA.; Institute for Systems Genomics, University of Connecticut, Storrs, CT 06296, USA., Medvedev P; Center for Medical Genomics, Pennsylvania State University, University Park, PA, USA.; Center for Computational Biology and Bioinformatics, Pennsylvania State University, University Park, PA, USA.; Department of Computer Science and Engineering, Pennsylvania State University, University Park, PA, USA.; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA., Makova KD; Department of Biology, Pennsylvania State University, University Park, PA, USA.; Center for Medical Genomics, Pennsylvania State University, University Park, PA, USA.; Center for Computational Biology and Bioinformatics, Pennsylvania State University, University Park, PA, USA., Vollmers C; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA., Carbone L; Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR 97239, USA.; Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA.; Division of Genetics, Oregon National Primate Research Center, Beaverton, OR 97006, USA.; Department of Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR 97239, USA., Green RE; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Jazyk:	angličtina
Zdroj:	The Journal of heredity [J Hered] 2023 Mar 16; Vol. 114 (1), pp. 35-43.
DOI:	10.1093/jhered/esac043
Abstrakt:	The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates. (© The American Genetic Association. 2022.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu