Diagnosis, Management and Prescription Practices of Adrenaline in Children with Food-Induced Anaphylaxis: Audit in a Specialized Pediatric Allergy Department.

Autor: Vamvakaris K; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece., Koumpoura A; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece., Farmaki M; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece., Lakoumentas J; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece., Pasioti M; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece., Papadopoulos N; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece.; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester M13 9PL, UK., Xepapadaki P; Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Thivon & Levadeias St., Goudi, GR-11527 Athens, Greece.
Jazyk: angličtina
Zdroj: Journal of personalized medicine [J Pers Med] 2022 Sep 09; Vol. 12 (9). Date of Electronic Publication: 2022 Sep 09.
DOI: 10.3390/jpm12091477
Abstrakt: In the era of evidence-based medicine, physicians worldwide should abide by universally approved practices and healthcare units should seek quality control and operational improvement. This audit evaluates the degree of compliance with the European Academy of Allergy and Clinical Immunology guidelines for the diagnosis and treatment of anaphylaxis in a pediatric Allergy Department. Medical records of 248 children with food-induced allergic reactions who presented both on emergency and outpatient basis were reviewed. Data were also collected from the e-prescription database and anaphylaxis severity was graded according to Sampson's criteria. An accuracy metric was used to calculate the consistency rate. Anaphylaxis was documented in 188/423 allergic reactions. The degree of agreement for the classification of the reactions as anaphylactic was 88.3%, while the respective rate for non-anaphylactic was 58.7%. In the anaphylactic cases, adrenaline was prescribed in 84.8%, while the respective rates for other drugs were: antihistamines: 27.6%; corticosteroids: 26.1%; inhaled β2-agonists: 11.8%. This study, through the example of pediatric food-induced anaphylaxis, underlines the significance of compliance to guidelines, organized documentation in healthcare units using specially formulated medical history forms and continuous medical stuff training. Thus, diagnosis and treatment practices can be improved for the benefit of patients.
Databáze: MEDLINE