Inflammatory Bowel Disease in Adult HIV-Infected Patients-Is Sexually Transmitted Infections Misdiagnosis Possible?

Autor: Siwak E; Department of Infectious and Tropical Diseases and Hepatology, Medical University of Warsaw, 02-091 Warsaw, Poland.; HIV Out-Patient Clinic, Hospital for Infectious Diseases, 02-091 Warsaw, Poland., Suchacz MM; Department of Infectious and Tropical Diseases and Hepatology, Medical University of Warsaw, 02-091 Warsaw, Poland.; Hospital for Infectious Diseases, 02-091 Warsaw, Poland., Cielniak I; HIV Out-Patient Clinic, Hospital for Infectious Diseases, 02-091 Warsaw, Poland., Kubicka J; HIV Out-Patient Clinic, Hospital for Infectious Diseases, 02-091 Warsaw, Poland., Firląg-Burkacka E; HIV Out-Patient Clinic, Hospital for Infectious Diseases, 02-091 Warsaw, Poland., Wiercińska-Drapało A; Department of Infectious and Tropical Diseases and Hepatology, Medical University of Warsaw, 02-091 Warsaw, Poland.; Hospital for Infectious Diseases, 02-091 Warsaw, Poland.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Sep 10; Vol. 11 (18). Date of Electronic Publication: 2022 Sep 10.
DOI: 10.3390/jcm11185324
Abstrakt: Background: The aim of our study was to describe 50 cases of inflammatory bowel disease (IBD) and HIV co-existence that are under medical supervision in Warsaw.
Methods: This was a retrospective descriptive study. Fifty HIV-infected patients, diagnosed with IBD during the years 2001-2019, were identified. IBD was diagnosed endoscopically and then confirmed by biopsy. All data was obtained from medical records.
Results: All studied patients were male with a median age of 33 years old (range 20-58 years). All, except one, were men who have sex with men (MSM). The median CD4 cell count was 482 cells/µL (range 165-1073 cells/µL). Crohn's disease (CD) was diagnosed in 7 patients (14%), ulcerative colitis (UC) in 41 patients (82%), and 2 patients (4%) had indeterminate colitis. Forty-nine patients (98%) reported a history of unprotected receptive anal intercourse and different sexual transmitted infections (STIs). Only in 10 patients (20%) were one or more IBD relapses observed.
Conclusions: We recommend HIV testing for every MSM with IBD suspicion. Moreover, STIs testing should be performed in every IBD patient with colorectal inflammation, using molecular and serological methods. Persons who reported unprotected receptive anal intercourse seem to have the biggest risk of STI-associated proctitis or proctocolitis mimicking IBD.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje