Survival study in early stages of glottis cancer, stratified by treatment.

Autor: Lois-Ortega Y; Department of Otorhinolaryngology, Obispo Polanco Hospital, Teruel, Spain., García-Curdi F; Department of Otorhinolaryngology, Obispo Polanco Hospital, Teruel, Spain., Vallés-Varela H; Department of Otorhinolaryngology, Lozano Blesa University Clinical Hospital, Zaragoza, Spain., Muniesa-Del Campo A; Faculty of Veterinary Sciences, Department of Animal Pathology, University of Zaragoza, Zaragoza, Spain.
Jazyk: angličtina
Zdroj: Acta oto-laryngologica [Acta Otolaryngol] 2022 Jul-Aug; Vol. 142 (7-8), pp. 627-633. Date of Electronic Publication: 2022 Aug 22.
DOI: 10.1080/00016489.2022.2110613
Abstrakt: Introduction: Squamous cell carcinoma (SCC) of the vocal cord in stages I or II can be treated with radiotherapy (RT) or transoral CO 2 laser microsurgery (TLM), with good oncological results.
Objectives: To study the survival of patients with SCC of the vocal cord in early stages, treated with RT or TLM, in a tertiary hospital.
Material and Methods: Disease-free survival (DFS), specific survival (SS), and overall survival (OS) were studied in patients diagnosed with stage I and II SCC of the vocal cord, for a span of 10 years of follow-up, based on sociodemographic characteristics of the patient and the primary treatment (TLM or RT).
Results: Both treatments achieved good survival rates. However, long-term SS was greater in patients treated with TLM compared to those treated with RT (91.7% vs. 50%, respectively, p  = .001). In addition, patients treated with TLM presented a higher OS in the short term than those treated with RT (99.0% vs. 89.1%, respectively. p  = .004).
Conclusions and Significance: Primary treatment with TLM obtained better results than RT in the survival of patients with SCC of the vocal cord in the early stages.
Databáze: MEDLINE
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