Acute urinary retention in men: 21-year trends in incidence, subsequent benign prostatic hyperplasia-related treatment and mortality: A Danish population-based cohort study.

Autor: Bengtsen MB; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark., Heide-Jørgensen U; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark., Borre M; Department of Urology, Aarhus University Hospital, Aarhus, Denmark., Knudsen JS; Department of Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark., Nørgaard M; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Jazyk: angličtina
Zdroj: The Prostate [Prostate] 2023 Jan; Vol. 83 (1), pp. 87-96. Date of Electronic Publication: 2022 Sep 20.
DOI: 10.1002/pros.24440
Abstrakt: Objective: To examine trends in incidence of acute urinary retention, subsequent benign prostatic hyperplasia-related treatment and mortality in the era of medical therapy for benign prostatic hyperplasia. Additionally, to compare mortality with the general population.
Materials and Methods: We conducted a Danish nationwide registry-based study including 70,775 men aged 45 years or older with a first hospitalization for acute urinary retention during 1997-2017. We computed annual standardized incidence rates, subsequent 1-year cumulative incidence of benign prostatic hyperplasia-related surgical and medical treatment, and standardized 3-month and 1-year mortality rates. Finally, we compared standardized all-cause and cause-specific mortality ratios with the general population.
Results: The standardized incidence rate of acute urinary retention per 1000 person-years increased transiently from 2.34 to 3.42 during 1997-2004, but gradually declined to 2.95 in 2017. The 1-year cumulative incidence of benign prostatic hyperplasia-related surgery declined from 31.2% to 19.8% and 20.5% to 7.7% after spontaneous and precipitated acute urinary retention, respectively. During 1997-2017, the standardized 1-year mortality declined from 22.2% to 17.2%. Compared with the general population, mortality was 4-5 times higher after 3 months and 2-3 times higher after 1 year of acute urinary retention. The cause-specific standardized mortality ratios were particularly high for deaths attributable to malignancies, urogenital disease, certain infections, chronic pulmonary disease, and diabetes.
Conclusion: During 1997-2017, we observed a transient increase in the incidence of acute urinary retention. The subsequent use of benign prostatic hyperplasia-related surgery declined considerably and mortality continued to be high, mainly because of deaths from malignancies, urogenital disease, infections, and preexisting comorbidity.
(© 2022 The Authors. The Prostate published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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