Synthesis of benzothiazole-appended bis-triazole-based structural isomers with promising antifungal activity against Rhizoctonia solani .
| Autor: | Upadhyay RK; Department of Chemistry, University of Delhi Delhi-110007 India rakeshkp@email.com., Saini KK; Department of Chemistry, University of Delhi Delhi-110007 India rakeshkp@email.com., Deswal N; Department of Chemistry, University of Delhi Delhi-110007 India rakeshkp@email.com., Singh T; Molecular Oncology Laboratory, Department of Zoology, University of Delhi, School of Life Sciences, JNU-Delhi India., Tripathi KP; Division of Agricultural Chemicals, Indian Agricultural Research Institute New Delhi India., Kaushik P; Division of Agricultural Chemicals, Indian Agricultural Research Institute New Delhi India., Shakil NA; Division of Agricultural Chemicals, Indian Agricultural Research Institute New Delhi India., Bharti AC; Molecular Oncology Laboratory, Department of Zoology, University of Delhi Delhi-110007 India., Kumar R; Department of Chemistry, University of Delhi Delhi-110007 India rakeshkp@email.com. |
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| Jazyk: | angličtina |
| Zdroj: | RSC advances [RSC Adv] 2022 Aug 30; Vol. 12 (37), pp. 24412-24426. Date of Electronic Publication: 2022 Aug 30 (Print Publication: 2022). |
| DOI: | 10.1039/d2ra04465j |
| Abstrakt: | In order to explore new antifungal agrochemicals, we reported the synthesis of two series 5a-f, 6 and 7a-f, 8 of benzothiazole-appended bis-triazole derivative-based structural isomers using a molecular hybridization approach. The synthesized compounds were tested for fungal growth inhibition against the plant pathogen Rhizoctonia solani . All the synthesized compounds showed excellent antifungal activity in their minimum concentrations (10-0.62 μM). Among all the synthetics, compounds 5b (ED Competing Interests: The authors do not have any conflict of interest. (This journal is © The Royal Society of Chemistry.) |
| Databáze: | MEDLINE |
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