Necrotizing Infundibular Crystalline Folliculitis-A Case Report of a Rare Entity and Review of the Literature.
| Autor: | Wiedemeyer K; Department of Pathology and Laboratory Medicine, University of Calgary, Cumming School of Medicine, Foothills Medical Centre, Calgary, Alberta, Canada., Brenn T; Departments of Pathology & Laboratory Medicine, and.; Medicine, Cumming School of Medicine, University of Calgary, Diagnostic and Scientific Centre, Calgary, Alberta, Canada., Naert K; Departments of Pathology & Laboratory Medicine, and.; Medicine, Cumming School of Medicine, University of Calgary, Diagnostic and Scientific Centre, Calgary, Alberta, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | The American Journal of dermatopathology [Am J Dermatopathol] 2022 Oct 01; Vol. 44 (10), pp. 774-777. Date of Electronic Publication: 2022 Jul 06. |
| DOI: | 10.1097/DAD.0000000000002239 |
| Abstrakt: | Abstract: Necrotizing infundibular crystalline folliculitis (NICF) is a rare distinct entity that was introduced in 1999. It typically presents with numerous eruptive waxy papules on the forehead and/or the upper back in adults in their fifth to seventh decade of life. The pathogenesis is unknown to date, but yeast and bacterial infection of the follicular ostia seems to contribute to the development. More recently, NICF has occasionally been observed as a side effect of targeted antitumoral therapy. Histopathologically, NICF is characterized by dilated follicular ostia filled with pale filamentous and birefringent material enclosed by parakeratotic columns of the epidermis and accompanied by a mild superficial inflammatory infiltrate of the dermis. This case report is about a 58-year-old male patient presenting with multiple eruptive keratotic papules on his forehead. Histopathology revealed all classic features of NICF. The case represents a classic example of NICF and is compared with previously published cases that are comprehensively summarized in this article. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2022 Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government.) |
| Databáze: | MEDLINE |
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