Impact of health-related quality of life on pediatric patients who underwent hematopoietic stem cell transplantation in a Colombian institution

Autor: Medina-Valencia D; Departamento Materno-infantil, Unidad de Trasplante de Médula Ósea, Fundación Valle del Lili, Cali, Colombia; Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia. trasplantemedulaoseapediatrico@fvl.org.co., Castillo-Martínez A; Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia; Departamento de Psiquiatría, Fundación Valle del Lili, Cali, Colombia. biomedica@ins.gov.co., Beltrán E; Centro de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia. biomedica@ins.gov.co., Manzi E; Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia; Centro de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia. biomedica@ins.gov.co., Chantre-Mostacilla A; Departamento Materno-infantil, Unidad de Trasplante de Médula Ósea, Fundación Valle del Lili, Cali, Colombia. biomedica@ins.gov.co., Guerrero-Fajardo GP; Departamento Materno-infantil, Unidad de Trasplante de Médula Ósea, Fundación Valle del Lili, Cali, Colombia. biomedica@ins.gov.co., Estacio M; Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia; Centro de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia. biomedica@ins.gov.co., Franco AA; Departamento Materno-infantil, Unidad de Trasplante de Médula Ósea, Fundación Valle del Lili, Cali, Colombia; Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia. biomedica@ins.gov.co.
Jazyk: English; Spanish; Castilian
Zdroj: Biomedica : revista del Instituto Nacional de Salud [Biomedica] 2022 Sep 02; Vol. 42 (3), pp. 531-540. Date of Electronic Publication: 2022 Sep 02.
DOI: 10.7705/biomedica.6403
Abstrakt: Introduction: Hematopoietic stem cell transplantation is the curative option for some diseases and is increasing patient survival. The health-related quality of life in these patients is not systematically evaluated. Objectives: The present study sought to describe the health-related quality of life and complications in children who underwent hematopoietic stem cell transplantation. Materials and methods: A cross-sectional study was conducted on pediatric transplanted survivors. Health-related quality of life was measured using the KIDSCREEN-27 scale and Short Form-12 (SF-12) in patients between 8 and 14 years of age and those over 14 years, respectively. Statistical analysis was performed using STATA 12 software. We used the Rasch model person parameter estimates translated into T-values to score the questionnaire. Results: A total of 42 children answered the questionnaires. The most frequent adverse events were chronic graft Vs. host disease and endocrine complications. According to European norm data in the KIDSCREEN-12 scale, scores for the school dimension and social and peer support were below the 50th. percentile. The group administered immunosuppressants had lower scores on the physical component of the SF-12™ scale. Conclusions: In general, the KIDSCREEN-27 does appear to suggest some quality-of-life deficit in younger children. The scales showed reliability in this population.
Databáze: MEDLINE
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