Acceptorless Dehydrogenation of Alcohols and Transfer Hydrogenation of Aldehydes in Water Using a Single Bifunctional, Bistate, Water-soluble Ruthenium Catalyst.

Autor: Hazra S; Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, 110016, India., Nair A; Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, 110016, India., Dolui P; Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, 110016, India., Malik E; Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, 110016, India., Elias AJ; Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, 110016, India.
Jazyk: angličtina
Zdroj: Chemistry, an Asian journal [Chem Asian J] 2022 Dec 01; Vol. 17 (23), pp. e202200883. Date of Electronic Publication: 2022 Oct 05.
DOI: 10.1002/asia.202200883
Abstrakt: A water-soluble bifunctional, bistate ruthenium catalyst has been developed using the 8-aminoquinoline ligand which responds to an acid-base stimuli and is catalytically active for two complementary reactions. The "Ru-amino state" is highly active for catalytic transfer hydrogenation of various aldehydes using formic acid as the hydrogen source resulting in a range of primary alcohols. On the other hand, the "Ru-amido state" is active for the acceptorless dehydrogenation of alcohols to yield carboxylate salts or ketones. The reactions can be carried out in air without an inert atmosphere and the products can be purified by simple extraction without the use of any chromatographic techniques. A range of functional groups which include electron-rich and deficient (hetero)arenes and alkenes, alkynes, halides, esters, cyano, and nitro groups, are all well tolerated, indicating excellent chemoselectivity for transfer hydrogenation.
(© 2022 Wiley-VCH GmbH.)
Databáze: MEDLINE
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