Sero-epidemiological survey of SARS-Cov2 in urban slums of a capital city: A cross- sectional study.

Autor: Nirala SK; Department of Community and Family Medicine, AIIMS, Patna, Bihar, India., Naik BN; Department of Community and Family Medicine, AIIMS, Patna, Bihar, India., Chaudhary N; Department of Community and Family Medicine, AIIMS, Patna, Bihar, India., Ranjan A; Department of Community and Family Medicine, AIIMS, Patna, Bihar, India., Mahto M; Department of Biochemistry, AIIMS, Patna, Bihar, India., Pandey S; Department of Community and Family Medicine, AIIMS, Patna, Bihar, India., Singh CM; Department of Community and Family Medicine, AIIMS, Patna, Bihar, India., Singh PK; Department of Anaesthesiology and Critical Care, AIIMS, Patna, Bihar, India.
Jazyk: angličtina
Zdroj: Journal of family medicine and primary care [J Family Med Prim Care] 2022 Jun; Vol. 11 (6), pp. 2709-2716. Date of Electronic Publication: 2022 Jun 30.
DOI: 10.4103/jfmpc.jfmpc_2127_21
Abstrakt: Introduction: Slums are the most vulnerable settlements for COVID-19 infection due to overcrowding and unsanitary conditions. Thus, this study was undertaken to determine the level of seroprevalence for SARS-CoV-2 infection among slum dwellers.
Material and Methods: A community-based cross-sectional seroepidemiological survey was conducted at several slums of Patna over four weeks, that is, January 20-February 20, 2021. A total of 650 participants were recruited in the study by applying a two-stage random sampling technique.
Results: Seroprevalence for SARS-CoV-2-specific IgG antibody was found to be 31.5% (95% Confidence Interval (CI): 27.9-35.1). The seropositivity prevalence was found to be statistically higher among participants belonging to the age group of 18-30 years (41.1%), male gender (67.9%), high-risk occupation (70%), below poverty line (BPL) economic status (62.1%), and residing in a hut (51.2%) and kutcha house (42.4%). Further, 262 participants reported having COVID-like symptoms in the preceding 1 month of the survey, which was found to be significantly associated with the seropositivity status.
Conclusion: The finding of the study reflects that a moderate seroprevalence level of COVID-19 infection was acquired in the slum settings of Bihar. Unchecked spread in these informal communities will pose a serious threat to the rest of the bigger sections of urban populations. This indirectly calls for early intervention in the form of preference in the roadmap of COVID-19 vaccination.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2022 Journal of Family Medicine and Primary Care.)
Databáze: MEDLINE
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